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Objective To observe the clinical efficacy of Cardiotonic Pill and Monopril in treating congestive heart failure disease. Methods Seventy-eight patients with congestive heart failure were randomly divided into two groups. The control group received routine treatment (Monopril), and the treated group were given Cardiotonic Pill besides routine treatment. The symptoms, physical signs and the parameter and classify of cardiac function were evaluated in all patients. Results The symptoms and physical signs after treatment were better than before. The cardiac function were improved. Comparison between the two groups showed difference (P
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Objective To observe the efficacy of Buyanghuanwu herbal decoctions on microalbuminur in noninsulin-dependent diabetes mellitus. Methods Sixty-six patients with noninsulin-dependent diabetes mellitus patients with 30～300 mg/24 h microalbuminur were randomly divided into the treated group (treated with Buyanghuanwu herbal decoctions) and the control group (treated with injection of Huangqi). The clinical efficacy was observed and levels of blood-fat, hemorheology and microalbuminur were determined. Results The levels of blood-fat, hemorbeology and microalbnminur were decreased in treated group. Comparison between the two groups showed significant difference (P
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[Objective] To study the effects of Buyang Huanwu Decoction and Radix Astragali on astrocytes in gerbils with cerebral ischemia and reperfusion injury. [Methods] Gerbils model of cerebral ischemia was set up by occlusion of bilateral common carotid arteries. The dynamic expression of glial fibrillary acidic protein (GFAP) were determined by immunohistochemical method in reperfusion for 24 and 48 hours after 15 minutes of cerebral ischemia. [Results] Positive expression of GFAP reached a peak in reperfusion for 24 hours and was decreased by Buyang Huanwu Decoction and Radix Astragali. Positive GFAP expression was attenuated in reperfusion for 48 hours and enhanced by Buyang Huanwu Decoction and Radix Astragali increased the expression. [ Conclusion ] The regulatory effect of Buyang Huanwu Decoction and Radix Astragali on astrocytes may be one of its mechanisms in repairing nervous function after cerebral ischemia.