ABSTRACT
AIM: To research Fufang Jingshu Tablet's(Rhizoma Chuanxiong,Radix Angelicae Dahuricae,Rhizoma Gastrodiae,Rhizoma Cibotii,Flos Chrysanthemi) pharmacological effect. METHODS: We used carrageenan-induced rat foot edema model and cotton pellet-induced granuloma model to observe the tablet's effect on inflammation,used analgesymeter to assess normal rats' and sciatic-nerve-stem-ligation rats' mechanical withdrawal thresholds,used inclined plane methods to assess the tablet's effect on general extremity strength of sciatic-nerve-stem-ligation model. RESULTS: The tablet could obviously reduce carrageenan-induced foot edema and cotton pellet-induced granuloma,elevate normal rats' mechanical withdrawal thresholds and decrease percent change of mechanical threshold of ipsilateral hind paws,elevate sciatic-nerve-stem-ligation rats' staying angle on inclined plane. CONCLUSION: Fufang Jiangshu Tablet has significant anti-inflammatory and analgesic effects. Furthermore it can improve the movement disfunction stemed from nerve compression significantly.