ABSTRACT
Objectives:To investigate the factors related to the long-term outcome for patients after severe traumatic brain injury. Methods:From January, 2015 to December, 2018, 135 patients with severe traumatic brain injury were selected. Their gender, age (of onset), education level, injury sites, and lesion side were recorded, and they were assessed with Disability Rating Scale (DRS), Mini-Mental State Examination (MMSE), Fugl-Meyer Assessment (FMA) for motor and balance and modified Barthel Index (MBI). They were assessed with DRS again one year after discharge. Results:The age (r = 0.188), early DRS score (r = 0.530), MMSE score (r = -0.376), FMA for motor (r = -0.284) and balance (r = -0.425) score, MBI score (r = -0.480), brain stem injury (r = 0.194) and diffuse brain injury (r = 0.202) were related to DRS scores as follow-up (P < 0.05); while, the gender (r = -0.175), early DRS score (r = 0.586), MMSE score (r = -0.242), FMA for motor (r = -0.301) and balance (r = -0.228) score, MBI score (r = -0.367) and occipital lobe injury (r = 0.209) were related to difference of DRS (P < 0.05). Conclusion:The age, early cognitive and motor dysfunction are related with the outcome of one year of patients after severe traumatic brain injury. More researches are needed to explore the impact of injury sites on the outcome.
ABSTRACT
<p><b>BACKGROUND</b>There has been a marked global increase in the incidence of human Campylobacter enteritis in recent years. This study investigated the epidemiological and clinical features of Campylobacter enteritis in adult patients suffering from acute diarrhea.</p><p><b>METHODS</b>This was a retrospective review of Campylobacter enteritis in adult patients with acute diarrhea presenting at Beijing University First Hospital, Beijing, China, in the summer and autumn (April to October) of 2005 to 2009. The data collected included the species of campylobacter identified, and the age, gender, clinical manifestations and results of laboratory test on stool samples collected from the patients. Campylobacter sensitivity tests to various antimicrobial agents were conducted on 80 specimens. Chi-square tests were applied using SPSS13.0 software and a two-sided P value of < 0.05 was considered statistically significant.</p><p><b>RESULTS</b>Campylobacter spp. isolated from the stool specimens of 142 patients with diarrhea represented 14.9% of all the cases examined. C. jejuni was identified in 127 patients (89.4%) and C. coli in 15 others (10.6%). The infection incidence was highest in the age range of 21 - 30 years which comprised 21.7% of the total cases examined. Most cases of diarrhea (46 patients) occurred in June. Watery diarrhea (97.2%), abdominal pain (72.5%) and fever (64.8%) were the most common manifestations of enteric campylobacteriosis. Only four patients (2.8%) had bloody diarrhea. The antimicrobial resistance rates were: cefoperazone (100%), levofloxacin (61.3%), gentamicin (12.5%), erythromycin (6.3%), and azithromycin (2.5%).</p><p><b>CONCLUSIONS</b>Campylobacter was prevalent among adults with acute diarrhea from 2005 to 2009 in Beijing, China. The large number of those afflicted by the disease warrants the commission of a large multicenter study to determine the extent of enteric campylobacteriosis in this region.</p>
Subject(s)
Adult , Female , Humans , Male , Middle Aged , Young Adult , Anti-Bacterial Agents , Therapeutic Uses , Campylobacter , Virulence , Campylobacter Infections , Drug Therapy , Microbiology , China , Diarrhea , Drug Therapy , Microbiology , Drug Resistance, Bacterial , Retrospective StudiesABSTRACT
<p><b>OBJECTIVE</b>To observe the effects of needle retaining on hemodynamic change and investigate the significance of retaining needle.</p><p><b>METHODS</b>Manual acupuncture was performed at the left Zusanli (ST 36) of 26 healthy adult volunteers who have not receiued acupuncture. 26 cases were randomly divided into a needle retaining group and a quick needling group, 13 cases in each group. Hemodynamic parameters of the anterior tibial artery were observed with color Doppler ultrasound before needling and 0, 1, 2, 3, 4 and 5 minutes after needle manipulation. Hemodynamic parameters were also compared between the two groups 0, 1, 2, 3, 4 and 5 minutes after needle manipulation.</p><p><b>RESULTS</b>There were no significant difference in V(max) and Vm between 0, 1, 2, 3, 4 and 5 minutes after needling manipulation (all P > 0.05).</p><p><b>CONCLUSION</b>Needle retaining can not change regional hemodynamic.</p>