Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 4 de 4
Filter
Add filters








Language
Year range
1.
Chinese Journal of Pediatrics ; (12): 793-797, 2012.
Article in Chinese | WPRIM | ID: wpr-348536

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the safety of treatment with ophthalmic artery cannulation for intra-arterial chemotherapy (IAC) for children with intraocular retinoblastoma (RB).</p><p><b>METHOD</b>In the RB Treatment Center of General Hospital of Armed Police Forces between January 2009 and September 2011, 42 patients who were diagnosed intraocular RB and treated with ophthalmic artery cannulation for IAC, 8 patients were treated 1 circle, 31 patients were treated 2 circles and 3 patients were treated 3 circles (total, 96 times). Each month had IAC once. The ophthalmic and the whole body evaluations were performed during IAC and after IAC for each circle, the blood cell count, alanine aminotransferase (ALT), serum creatinine (Scr), CK-MB content before and after IAC for 1 circle, 2 circles and 3 circles were determined.</p><p><b>RESULT</b>(1) In 52 eyes of 42 patients, 44 eyes (84.6%) were in remission. (2) Successful IAC was achieved in all cases, no severe side effects occurred during IAC. (3) The main ophthalmic complications were eyelid edema and blepharoptosis after IAC, the incidence for 1 circle was 18% (2/11) and 9% (1/11); for 2 circles was 29% (11/38) and 21% (8/38); for 3 circles was all 100% (3/3). The rare complications were vitreous hemorrhage and heterotropia, the incidence was all 2% (1/42). The incidence of eyelid edema and blepharoptosis had no significant differences for 1 circle IAC compared with 2 circles (P > 0.05); the incidence of eyelid edema and blepharoptosis had significant differences for 3 circles IAC compared with 2 circles and 1 circle (P < 0.01). (4) No fever, septicemia and other systemic toxic effects occurred. (5) ALT of 19% patients (8/42) elevated temporarily and CK-MB of 24% patients (10/42) increased. The blood cell counts, ALT, Scr, and CK-MB content before IAC had no significant differences compared with that at 24 h after IAC for 1 circle, 2 circles and 3 circles (P > 0.05).</p><p><b>CONCLUSION</b>Ophthalmic artery cannulation for IAC is a safe and effective method in treating intraocular stage retinoblastoma.</p>


Subject(s)
Child, Preschool , Female , Humans , Infant , Male , Antineoplastic Agents, Alkylating , Therapeutic Uses , Catheterization , Methods , Infusions, Intra-Arterial , Liver Function Tests , Melphalan , Therapeutic Uses , Neoplasm Staging , Ophthalmic Artery , Postoperative Complications , Epidemiology , Retinal Neoplasms , Drug Therapy , Pathology , Retinoblastoma , Drug Therapy , Pathology , Retrospective Studies , Treatment Outcome
2.
Ophthalmology in China ; (6)2006.
Article in Chinese | WPRIM | ID: wpr-680217

ABSTRACT

2cm~2.Conclusions The auto-cranial pedicle flap via endonasal repairing blow-out fractures of or- bital inferior wails is an effective technique.The results are good for improving eye movement especially for fracture ranged≤2cm~2. (Ophthalmol CHN,2007,16:388-390)

3.
China Journal of Chinese Materia Medica ; (24): 737-739, 2004.
Article in Chinese | WPRIM | ID: wpr-272814

ABSTRACT

<p><b>OBJECTIVE</b>To ascertain extraction technology condition for extract and flavonoids from Chrysanthum morifoliwn.</p><p><b>METHOD</b>The optimizing ultrasonic extraction condition on the basis of extractive yield and flavonoids were determined by orthogonal design.</p><p><b>RESULT</b>The order of factors which affected the flavonoid extraction was extraction times > ethanol concentration > ultrasonic time > solvent quantity.</p><p><b>CONCLUSION</b>The optimum ultrasonic extractions are A2B3C3D3. Compared with traditional extraction, ultraction method is timesaving, simple to operate, stable and need not be heated.</p>


Subject(s)
Chrysanthemum , Chemistry , Drugs, Chinese Herbal , Flavonoids , Flowers , Chemistry , Plants, Medicinal , Chemistry , Technology, Pharmaceutical , Methods
4.
China Journal of Chinese Materia Medica ; (24): 424-425, 2004.
Article in Chinese | WPRIM | ID: wpr-256338

ABSTRACT

<p><b>OBJECTIVE</b>To optimize the ultrasonic extraction condition for flavonoids from Chrysanthemum morifolium.</p><p><b>METHOD</b>The extraction rate of flavonoids optimized condition (ethanol concentration, ultrasonic time, solvent quantity and extraction times) was determined by orthogonal design. UV-Spectrophotometry was used for the determination.</p><p><b>RESULT</b>The order of factors to affect the flavonoid extraction was ethanol concentration > extraction times > solvent quantity > ultrasonic time.</p><p><b>CONCLUSION</b>The optimum ultrasonic extractions were: A2 B2 C3 D3. Compared with traditional extraction, ultraction method can save time, be easy to operate, improve extraction rates and need no heating.</p>


Subject(s)
Chrysanthemum , Chemistry , Flavonoids , Plants, Medicinal , Chemistry , Technology, Pharmaceutical , Methods , Ultrasonics
SELECTION OF CITATIONS
SEARCH DETAIL