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Journal of Clinical Hepatology ; (12): 2584-2588, 2020.
Article in Chinese | WPRIM | ID: wpr-829647

ABSTRACT

Nonalcoholic fatty liver disease (NAFLD) and hypertension are both important components of metabolic syndrome, and there is a strong association between these two diseases. This article analyzes the association between NAFLD and hypertension based on clinical data and describes the common pathogeneses of the two diseases, among which insulin resistance, gut microbiota, renin-angiotensin-aldosterone system play an important role in the pathogenesis of these two diseases. In addition, this article briefly summarizes the application of renin-angiotensin-aldosterone system inhibitors and diuretics in the treatment of NAFLD, which provides a reference for further clarifying the association between these two diseases, understanding the mechanism of interaction between the two diseases, and exploring the treatment methods for NAFLD with hypertension.

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