ABSTRACT
Biology-guided radiotherapy (BgRT) is a novel technique of external beam radiotherapy, combining positron emission tomography-computed tomography (PET-CT) with a linear accelerator (LINAC). The key innovation is to utilize PET signals from tracers in tumor tissues for real-time tracking and guiding beamlets. Compared with a traditional LINAC system, a BgRT system is more complex in hardware design, software algorithm, system integration and clinical workflow. RefleXion Medical has developed the world's first BgRT system. Nevertheless, its actively advertised function, PET-guided radiotherapy, is still in the research and development phase. In this review study, we presented a number of issues related to BgRT, including its technical advantages and potential challenges.
Subject(s)
Positron Emission Tomography Computed Tomography , Radiotherapy Planning, Computer-Assisted/methods , Algorithms , Particle Accelerators , Biology , Radiotherapy, Image-Guided/methods , Radiotherapy DosageABSTRACT
This discussion attempts to organize and analyze the clinical purpose of various technologies developed by medical electron accelerators from the development history and clinical needs of radiotherapy products, so as to avoid the troubles caused by specific technical details and summarize the development of medical accelerators. Directly, the study provides differentiated development ideas for the development of domestic medical accelerators and ways and means to determine the dimensions of differentiated development.
Subject(s)
Particle Accelerators , Protective DevicesABSTRACT
This discussion attempts to organize and analyze the clinical purpose of various technologies developed by medical electron accelerators from the development history and clinical needs of radiotherapy products, so as to avoid the troubles caused by specific technical details and summarize the development of medical accelerators. Directly, the study provides differentiated development ideas for the development of domestic medical accelerators and ways and means to determine the dimensions of differentiated development.