ABSTRACT
Objective To study the relationship between the concentration of oxidized low density lipoprotein(Ox-LDL)and ca-rotid intima-media thickness(IMT)in acute cerebral infarction(ACI group).Methods 44 ACI patients(ACI group)and 30 healthy individuals(control group)were enrolled in the study,whose serum concentrations of Ox-LDL were determined by using enzyme-linked immunosorbent assay(ELISA),and carotid IMT of ACI patients were measured by using ultrasound,then the relationship between Ox-LDL and carotid IMT of ACI patients was analysed.Results The serum concentration of Ox-LDL in ACI group was significantly higher than that in control group(P <0.01).In ACI group,the serum concentration of Ox-LDL was positively correla-ted with carotid IMT(r =0.493,P <0.05 ).In ACI group,the serum Ox-LDL concentrations of patients whose IMT≥1.0 were higher than patients whose IMT<1.0 mm(P <0.05).Ox-LDL concentrations of ACI patients were positively correlated with the carotid IMT(r =0.493,P <0.05 ).Conclusion The serum concentration of Ox-LDL increased significantly in ACI patients,and was closely related to carotid atherosclerosis.