ABSTRACT
A 38‑year‑old male presented with a 2‑week history of sudden blurred vision (best‑corrected visual acuity: 20/200) and pain in his right eye. Spectral domain optical coherence tomography (OCT) revealed focal thickening of the retinal pigment epithelium layer as leopard spots [Fig. 1a]. Fundus examination demonstrated exudative retinal detachment and retinal vascular dilation [Fig. 1c] whereas the contralateral eye remained unremarkable [Fig. 1b and d]. B‑scan ultrasonography showed a short axial length (17.3 mm). Fundus fluorescein angiography and indocyanine green angiography revealed leopard spots of granular hyperfluorescence in the posterior and inferior quadrants [Fig. 1e], which were increased with time and persisted until the late phase [Fig. 1f]. On the basis of clinical findings, we diagnosed him and it revealed to be nanophthalmic uveal effusion syndrome (UES).[1] After 10 mg dexamethasone was applied intravenously, two‑third thickness scleral flaps measuring 4 mm × 5 mm were performed at inferotemporal and inferonasal sites [Fig. 2a]. Under them, the remaining sclerae were excised measuring 1 mm × 2 mm accordingly [Fig. 2b and c]. Biopsy [Fig 2d] and pathologic evaluation revealed fibroblastic proliferation and hyaline degeneration of lamellar sclera [Fig. 2e and f]. The effusion was not detected at least on 6‑month follow‑up [Fig. 3], and the visual acuity was stabled at 20/100.