ABSTRACT
Objective:To analyze clinical features and imaging characteristics of cryptogenic organizing pneumonia (COP) confirmed by pathological examination, and improve clinicians understanding of the disease and reduce the disease misdiagnosis. Methods:General information, clinical manifestations,laboratory examination and radiographic features of 25 patients with COP confirmed by pathological examination of lung biopsy were collected, and a comprehensive analysis of these data was made. Results:There were 15 males and 10 females in 25 patients.The mean age was (61.4±13.1) years.And 6 cases (24??0%) had smoking history. All patients had no obvious allergic and industrial dust related exposure history. The clinical presentations were nonspecific, and the main clinical symptoms were cough with a small amount of sputum. The most common laboratory tests was counting normal white blood cells and faster blood sedimentation.The main features of chest CT were space occupying lesions and patchy consolidation or ground-glass opacification.Conclusion:The clinical manifestation and laboratory examination of COP lack of characteristic, and the chest CT performance is similar to tumor and lung infection, and the diagnosis of COP depends on pathological examination.In order to reduce misdiagnosis,clinical doctors should improve the awareness and vigilance of the disease.