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1.
Journal of Biomedical Engineering ; (6): 18-22, 2016.
Article in Chinese | WPRIM | ID: wpr-357858

ABSTRACT

Intraocular pressure detection has a great significance for understanding the status of eye health, prevention and treatment of diseases such as glaucoma. Traditional intraocular pressure detection needs to be held in the hospital. It is not only time-consuming to doctors and patients, but also difficult to achieve 24 hour-continuous detection. Microminiaturization of the intraocular pressure sensor and wearing it as a contact lens, which is convenient, comfortable and noninvasive, can solve this problem because the soft contact lens with an embedded micro fabricated strain gauge allows the measurement of changes in corneal curvature to correlate to variations of intraocular pressure. We fabricated a strain gauge using micro-electron mechanical systems, and integrated with the contact lens made of polydimethylsiloxane (PDMS) using injection molding. The experimental results showed that the sensitivity was 100. 7 µV/µm. When attached to the corneal surface, the average sensitivity of sensor response of intraocular pressure can be 125.8 µV/mm Hg under the ideal condition.


Subject(s)
Humans , Contact Lenses, Hydrophilic , Dimethylpolysiloxanes , Glaucoma , Intraocular Pressure , Tonometry, Ocular
2.
Journal of Biomedical Engineering ; (6): 967-970, 2014.
Article in Chinese | WPRIM | ID: wpr-234475

ABSTRACT

Brain-computer interface (BCI) system is a system that achieves communication and control among humans and computers and other electronic equipment with the electroencephalogram (EEG) signals. This paper describes the working theory of the wireless smart home system based on the BCI technology. We started to get the steady-state visual evoked potential (SSVEP) using the single chip microcomputer and the visual stimulation which composed by LED lamp to stimulate human eyes. Then, through building the power spectral transformation on the LabVIEW platform, we processed timely those EEG signals under different frequency stimulation so as to transfer them to different instructions. Those instructions could be received by the wireless transceiver equipment to control the household appliances and to achieve the intelligent control towards the specified devices. The experimental results showed that the correct rate for the 10 subjects reached 100%, and the control time of average single device was 4 seconds, thus this design could totally achieve the original purpose of smart home system.


Subject(s)
Humans , Brain-Computer Interfaces , Electroencephalography , Evoked Potentials, Visual , Microcomputers , Wireless Technology
3.
Journal of Biomedical Engineering ; (6): 421-427, 2013.
Article in Chinese | WPRIM | ID: wpr-234638

ABSTRACT

We studied the interaction between proteins and polystyrene-polyacrylic acid (PS-PAA) spherical polyelectrolyte brushes with different polyacrylic acid (PAA) chain lengths, including the physical adsorption and chemical adsorption in PBS buffer. Results showed that the amount of bovine serum albumin (BSA) physically adsorbed on PS-PAA spherical polyelectrolyte brushes decreased to a minimum of 33 microg/mg whereas the amount of streptavidin (SA) chemically adsorbed increased with the increase of chain length and carboxyl quantity. The biotin binding capacity of streptavidin chemically adsorbed on PS-PAA spherical polyelectrolyte brushes was roughly evaluated via enzyme competitive inhibition.


Subject(s)
Acrylic Resins , Chemistry , Adsorption , Biosensing Techniques , Electrochemical Techniques , Methods , Electrolytes , Chemistry , Polyamines , Polymers , Chemistry , Polystyrenes , Chemistry , Proteins , Chemistry , Serum Albumin, Bovine , Chemistry , Surface Properties
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