ABSTRACT
Objective To study the expression of the long non-coding RNA-BC043614 in pancreatic ductal adenocarcinoma (PDAC) and to analyse the relationship between the clinical pathological data and the prognosis of PDAC.Methods The clinical data of 42 patients who had PDAC treated from June 2013 to June 2014 were retrospectively analyzed.Real-time fluorescence quantitative PCR (qRT-PCR) was performed to detect the difference in expression of lncRNA-BC043614 between PDAC and its adjacent normal tissues.Correlation between the expression of lncRNA-BC043614 in PDAC and the clinical pathological characteristics was analyzed by the x2 test.The potential of lncRNA-BC043614 in predicting prognosis in patient with PDAC after operation was assessed using the Log-rank test and the Cox's proportional hazards regression model.Results The expression of lncRNA-BC043614 was markedly higher in PDAC than in its adjacent normal tissues (P ＜0.05).The expression of lncRNA-BC043614 in PDAC was significantly correlated with tumor size,tumor differentiation,vascular carcinoma,and CA19-9 serum levels (P ＜ 0.05).Patients with a higher expression of lncRNA-BC043614 in PDAC had a significantly shorter tumor-free survival (P ＜0.05).A high expression of lncRNA-BC043614 in PDAC was an independent risk factor of tumor-free survival in patients with PDAC after operation (P ＜ 0.05).Conclusions lncRNA-BC043614 was highly expressed in pancreatic cancer tissue and it correlated with the patient's tumor-free survival.lncRNA-BC043614 can be used as a new prognostic biomarker.
ABSTRACT
Objective To investigate the efficacy of transvaginal myomectomy(TVM) and abdominal myo-mectomy(TAM) in treatment of hysteromyoma.Methods 70 patients with hystemmyoma were separated into 2 groups randomly.Patients in the control group received TAM and patients in the observe group were managed with TVM.The operation time,blood loss in operation,time of gas passage by anus and the highest temperature after opera-tion of the 2 groups were analyzed.The prevalence after operations and use rate of acesodyne were evaluated.Results The operation time,blood loss in operation,time of gas passage of TVM group were significantly lower than that of TAM group.The use rate of acesodyne in TAM group was significantly higher than that of TVM group(P<0.01).However,the difference of the prevalence after operations between two group was not significant(P>0.05).Conclu-sion Compared with TAM,TVM had better clinical effects in treating hysteromyoma.
ABSTRACT
Currently, transgenic crops create huge economic, social and ecological benefits with the development of its commercial production. For China, the speed of development and commercialization of transgenic crops is a strategic issue for the sustainable agriculture development and the international competitiveness of our agricultural products. In this paper, we compared and analyzed the status of commercialization of transgenic crops in China and world-wide.