unusual renal ttimor: low-grade mucinous tubular and spindle cell carcinoma

Low-grade mucinous tubular and spindle cell carcinoma is a rare tumor which was described in the 2004 OMS Classification as a new entity. We report the case of a 42-year-old female patient presenting with chronic lower back pain on the left side. On CT scan a left renal mass of 10 cm in diameter was seen, and the patient underwent left radical nephrectomy. Macroscopic examination of the resected organ revealed a well-defined, fleshy, partly hemorrhagic and necrotic tumor on the medial aspect of the kidney, measuring 8.2 cm in diameter. Microscopic evaluation confirmed the diagnosis of a non-infiltrating mucinous tubular carcinoma with spindle cells not invading the hilum. Histopathologic studies revealed positive staining for CK [KL1], CK7, CK20, EMA, vimentin and CD 15 and negative staining for CD 10. Our case report of this rare entity aims to draw the attention of pathologists and clinicians to the importance of its diagnosis, in view of its favorable prognosis

[Squamous cell carcinoma of the pelvis presenting as pyonephrosis. A case report and review of the literature]

Squamous cell carcinoma of the renal pelvis is a rare tumor with a poor prognosis, mainly occurring in patients with neglected and secondarily infected pyelocalyceal stones. We report a new case of a 45-year old man who presented with features of pyonephrosis and was subjected to nephrectomy. Post-operative histological evaluation revealed an unsuspected squamous cell carcinoma of the renal pelvis. The patient died 3 months after the operation. Based on our observation and a review of the literature, we discuss the etiopathogenesis, histological, clinical and therapeutic aspects of this pathology