Transcerebral inter ventricular versus subcutaneous clonidine on some kidney functions in rats

The aim of the present work was to evaluate the effect of clonidine on some renal functions after transcerebral intraventricular [t.i.v.] and subcutaneous [s.c.] injection in the rats. The study was carried out on 60 young adult male albino rats divided into six groups, each consists of 10 rats according to the route of clonidine administration, its dose, and whether phentolamine was injected prior to s.c. clonidine administration or not. The results showed that clonidine injection whether s.c. in a dose of 60 ug/kg body weight or t.i.v. In a dose of 1 ug/kg body weight caused significant diuresis, natriuresis, increase chloride excretion, decrease urine osmolality and reduction in urinary creatinine, while serum osmolality significantly increased

Concomitant trigeminal involvement in Bell's palsy

Fifty patients [25 males and 25 females] with acute unilateral Bell's palsy were included in this study. Their average age was 36.3 years. Facial pains in the paretic side was experienced by 15 [30%] of the cases. Clinical evidence of trigeminal dysfunction on the paretic side was encountered in 24% of the cases. The facial latency of the contralateral side was prolonged in 8% of the patients [subclinical facial palsy]. Abnormal blink reflex pattern indicative of trigeminal nerve dysfunction was demonstrated in 36% of the patients [i.e. prolonged contralateral late response]. The results of this study drew the attention to the fact that Bell's palsy is a manifestation of polyneuritis cranialis and as well to the important role of blink reflex as a simple non invasive electrodiagnostic method to detect any dysfunction along trigemino-facial reflex arc