ABSTRACT
Objective To study the chemical constituents of the rhizome of Sinacalia tangutica. Methods The constituents were isolated and purified by silica gel, polyamide column chromatography, Sephadex LH-20, and ODS column chromatography. Their structures were elucidated by NMR spectra comparison with reference data. Results Fourteen phenolic compounds were isolated from the rhizome of S. tangutica, which were identified as hydrangetin (1), 7-hydroxy-coumarin (2), syringic acid (3), 4-hydroxy-3,5-dimethoxybenzaldehyde (4), 3,4-dihydroxybenzaldehyde (5), 4-hydroxybenzaldehyde (6), caffeic acid (7), p-hydroxycinnamic acid (8), ferulic acid (9), methyl 4-O-caffeoyl quinate (10), methyl 5-O-caffeoyl quinate (11), ethyl 5-O-caffeoyl quinate (12), methyl 4,5-di-O-caffeoyl quinate (13), and methyl 3,5-di-O-caffeoyl quinate (14). Conclusion Compounds 3-5, 7-14 are isolated from the genus of Sinacalia for the first time.