Hypokalemic Rhabdomyolysis — A Rare Presentation

Hypokalemia leading to Rhabdomyolysis is a potentially fatal disorder if not identified and treated early. In this case report we present a patient who had one week history of asymmetric painful Quadriparesis with neck drop and preserved reflexes. Evaluation revealed Hypokalemia with raised creatine.

Critical Review of Ayurvedic and Contemporary Concept of Dushi Visha and its Treatment

Poisoning is a major public health concern that is becoming more common by the day. Poison can be consumed directly or indirectly from a variety of sources. Poisoning can now be found in a variety of areas, including junk food with chemical preservatives, various sorts of growing products like rice and wheat, and pesticide-laced veggies. As a result of diverse human behaviours, water, air, and soil have become contaminated, posing a hazard to human health. According to Ayurvedic doctrine, there are several sources of obtaining of toxins i.e., either through animate, inanimate or Kritim(artificial). Such toxins are accumulated without eliminating through the body or remains with being the less potent inside the body for several years generally called Dushi Visha. All the sign and symptoms of Dushi Visha looks like that of chronic poisoning and varies from organs to organs, where it becomes deposited. Such accumulated Visha then vitiates Dosha and that leads to vitiation of different kinds of Dhatus respectively. like, Rakta Dusti, Kitiva, Vrana, Kotha are the major manifestations that will see after prolong exposure to Dushi Visha. The main line of treatment of Dushi Visha is through Detoxification (i.e., Vamana, Virechana, Raktamokshana karma) followed by Dushivisari Agad Paana, that has mentioned by Charak. Classical text book has mentioned different level of clinical manifestations including sign and Symptoms and its complication along and its management with specific Justification.

Endoscopic Diagnosis, Screening and Surveillance and Treatment of Barrett’s Esophagus: An Overview.

Barrett’s esophagus (BE) is an acquired condition in which the squamous epithelial lining of the lower esophagus is replaced by a columnar epithelium due to chronic gastroesophageal reflux. The prevalence of BE has ranged from 0.9% to 4.5%. The rate of progression from BE to esophageal adenocarcinoma is 0.5% per patient-year. Human studies show that the reflux of bile parallels acid reflux and increases with the severity of gastroesophageal reflux disease (GERD), being most marked in BE. However, recent ex vivo studies suggest that pulses of acid reflux may be more important than bile salts in the development of dysplasia or adenocarcinoma in Barrett’s epithelium. The diagnosis of BE can be suspected when, during endoscopic examination, columnar epithelium is observed to extend above the gastroesophageal junction (GEJ) into the tubular esophagus. Although, guidelines for the diagnosis, surveillance and management of BE were published, the main goal in the management of premalignant condition would be the permanent elimination of Barrett’s mucosa. Current therapeutic options are limited or still in the investigational stages. This review summarizes the endoscopic diagnosis, screening, surveillance and introduces endoscopic ablative modalities currently used.