ABSTRACT
Aneurysmal bone cyst is a relatively rare tumour accounting 1 to 6% of all primary bone tumours. The involvement of clavicle is even rare with incidence of only 3% of all cases of aneurysmal bone cyst. Aneurysmal bone cyst is an expanding osteolytic lesion occurring mostly at metaphyseal ends of the long bones. Although excisional biopsy is diagnostic for aneurysmal bone cyst and FNAC (fine needle aspiration cytology) is mostly inconclusive. Still FNAC can be helpful in pre-operative diagnosis of aneurysmal bone cyst.
Subject(s)
Adolescent , Biopsy, Fine-Needle , Bone Cysts, Aneurysmal/diagnosis , Clavicle , Humans , MaleABSTRACT
Malignant peripheral nerve sheath tumour (MPNST) is a relatively rare tumour arisingfrequently in patients with neurofibromatosis, type I (NF1). It is usually a high grade sarcoma. A 65 year old female patient presented with a swelling in left popliteal fossa of two months duration. She had multiple nodular lesions all over the body since childhood. She was subjected to fine needle aspiration for the popliteal mass and was reported as MPNST which was confirmed on histopathology. She developed recurrence within four months time. The prognosis of MPNST is poor. Fine needle aspiration cytology is a very useful, rapid sensitive and inexpensive investigative procedure for the diagnosis of soft tissue tumours and can replace an open biopsy for the diagnosis of MPNST in patients with neurofibromatosis-1.
Subject(s)
Biopsy, Fine-Needle , Female , Humans , Middle Aged , Nerve Sheath Neoplasms/diagnosis , Neurofibromatosis 1/pathology , Soft Tissue Neoplasms/diagnosisABSTRACT
A 58 years old male came with a painful swelling in right gluteal region. On examination a small mass was found which was subsequently excised. Histopathological study reported presence of presumptive schwannomatosis, as there were 4 tumours composed of Antoni A and Antoni B areas along with Verocay bodies. As post-operative MRI scan of base of brain and ophthalmological examination of patient failed to reveal vestibular schwannomas and ocular stigmata of neurofibromatosis type 2 (NF-2) respectively, a final diagnosis of definite schwannomatosis was made.