ABSTRACT
BACKGROUND: Colorectal cancer is a common, deadly disease with different incidence rates in different parts of the world. The present study aims to investigate the clinical presentations, colonoscopic findings, and family history of colorectal cancer in the city of Khorramabad, Iran
METHODS: This cross-sectional study, conducted in 2013, included 112 patients diag-nosed with colorectal cancer by colonoscopy with pathological confirmation in addition to 112 individuals matched with patients for age and gender. Controls were chosen from the outpatients admitted to the Skin and Eye Clinics of Sho-hadaAshayer Hospital in Khorramabad who had no gastrointestinal diseases. A self-generated questionnaire was used to assess family history of smoking and gastrointestinal cancer history in immediate relatives of subjects from both groups. Fisher's exact test and odds ratios [OR] were used to analyze the data
RESUETS: Based on the findings of this study, the most common clinical presentation in the patients was abdominal pain [67.9%]
The sigmoid colon [40%] was the most common anatomical site of the tumor in men; the rectum [34.6%] and sigmoid colon [34.6%] were the most common sites in women, which was not statistically significant [p=0.21]
There were 11 [19.6%] patients and 2 [3.6%] individuals in the control group who reported a history of colorectal cancer in their immediate relatives, which was statistically significant [p=0.008]
CONCEUSION: In this study, left-sided colon cancer was more common. Subjects with colon cancer had more [positive FHx. This indicated that genetic factors, in addition to environmental factors, could increase the incidence of colorectal cancer in a community. A better identification of these factors would result in better control and management of this disease
ABSTRACT
Hallux valgus or the lateral deviation of the great toe is a complex disease. If it is not treated, it will cause the deviation of other toes. Hallux valgus is three times more common in females and may cause uncomfortable deformity of the foot, problems in putting on unsuitable and narrow toe box shoes, and pain on the medial side of the first metatarsophalangeal joint; therefore, patients seek medical services. Untreated hallux valgus may cause the hammer toe deformity of the second toe. In this cohort study, 30 patients referring to the Orthopedic Clinic of Shohada Ashayer Hospital of Khorramabad, Iran, with a complaint of hallux valgus were randomly divided into two groups. The splints designed by the researches [slippers splints] were given to the case group, and the splints on the market including night splints and interdigital pads were given to the control group. The patients were followed every three months for a year and every time the weight bearing anteroposterior radiography of both feet were taken and hallux valgus and inter-metatarsal angles were measured. The data was analyzed by the SPSS software using repeated measure tests. In the case group that used the designed splints regularly, hallux valgus angles decreased more dramatically than in the control group [P<0.001]. This study showed that, despite controversies over the nonoperative treatment of hallux valgus, if hallux valgus angle in patient is mild to moderate, the splint can be used as a nonoperative treatment