ABSTRACT
Background: Diabetes is one of the main causes of neuropathy. Metabolic control is essential to hinder its process. The present study was designed to investigate the effect of aerobics training on metabolic control in type-2 diabetic men with peripheral neuropathy
Methods: Twenty-four male subjects with Type 2 Diabetes were randomly assigned into two groups [each group comprised of 12 subjects]: 1- Aerobics training [43+/-6.4 yrs, 86.5+/-15.3 kg] 2- control [42+/-4.6 yrs, 89.3+/-11.9 kg]. Aerobics training consisted of 20 to 45 minutes walking and running with 50 to 75 percent of heart rate reserve, three sessions per week for 3 months. Before and 48h after last training session, body composition measurements were performed and then fasting and aftermeal blood samples were taken
Results: We observed no significant changes in weight, fat percentage and body mass index following intervention [P>0.05]. Furthermore, fasting and OGTT glucose and HbA1C levels significantly decreased and lipid profile improved significantly [P<0.05]. We also observed significant inter-group difference only for HbA1C and HDL-C [P<0.05]
Conclusion: Based on the findings of the present study, it could be concluded that aerobic exercise regimen could be a safe non-pharmacological strategy to achieve an optimal metabolic control in type-2 patients with peripheral neuropathy
ABSTRACT
Backgrounds and Objectives: Acute poliomyelitis is now an uncommon disease but its long term morbidities are still a challenge. Post polio syndrome includes new neuromuscular symptoms that polio survivors are often confronted with several years after acute polio. The purpose of this study was to assess quality of life, and physical and psychological function in persons with postpolio syndrome [PPS]
Materials and Methods: 204 subjects with history of poliomyelitis were recruited in this cross sectional study. Finally, 52 people affected by post polio syndrome were compared with 50 healthy people [as control group] regarding the quality of life, and physical and psychological function. Utilized assessment instruments were: 36-Item Short Form Health survey [SF-36] and its two physical functioning and mental health subscales, visual analogue scale, fatigue severity scale and muscle manual muscle testing. The data were analyzed using mean and standard deviation, Independent t test, Kruskal-Wallis test and multivariate regression test. The level of significance was set at 0.05
Results: The mean age of patients in this study was 41.65 +/- 8.74. Comparing the patients with control group revealed that the patients reported a poorer quality of life, and physical and psychological function. Multivariate analyses identified that physical function was affected by muscle weakness, while psychological function was affected by pain and fatigue
Conclusion: Quality of life, and physical and psychological function of people with PPS were reduced. These patients need support from multidisciplinary teams to cope with new neuromuscular problems