ABSTRACT
Background: Tympanosclerosis is one of complications of chronic otitis media with accumulation of hyaline and calcified deposits intra tympanic membrane and middle ear's membrane. In most cases these plaques are of minimal clinical significance and result in trivial hearing dysfunction
Methods: 60 patients diagnosed with chronic otitis media and tympanosclerosis who were candidates for operation and met inclusion criteria were evaluated. Audiometric evaluations were assessed before and after surgery. Intra operative findings and Post operative clinical results were also evaluated after surgery
Results: 25[43.1%] patients were male and 33[56.9%] were female. Hearing dysfunction was monolateral in 62.1% and bilateral in 37.9%. The most common location of ossicular chain fixation is between incus and malleus reported in 24[41.3%] patients
Conclusion: Middle ear surgery result is astonishing although other factors such as severity of sclerosis and fixation localization may also be influential in surgical results
ABSTRACT
Background: Attention deficit hyperactivity disorder [ADHD] is one of the most common mental diseases in children. Fatty acids are important components of nerve cell myelin. Essential fatty acid deficiency leads to behavioral abnormalities similar to nervous disorders, such as ADHD. The purpose of this study was to determine the composition of fatty acids in plasma phospholipids and whole erythrocyte in the ADHD boys
Methods: This is a case-control study in which 36 boys with ADHD and 37 boys without ADHD -aged 6-12 years- were participated. ADHD children were diagnosed with clinical diagnosis and psychiatric questionnaires by a psychiatrist. Then fatty acids of plasma phospholipids and whole erythrocyte were extracted
Results: The mean content of sum of saturated fatty acids [P=0.004] and arachidonic acid [P<0.001] of plasma phospholipids were significantly lower and mean concentrations of oleic acid [P<0.001] and sum of monoenes [P<0.001] were significantly higher in the ADHD group compared to the control one. However in the total RBC, the mean concentrations of stearic acid [P=0.003], arachidonic acid [P=0.04] and alpha-linolenic [P=0.02] acid were significantly lower and the mean content of linoleic acid [P=0.01] was significantly higher in the ADHD group compared to the control one
Conclusion: Fatty acid composition of plasma phospholipids and RBC in the ADHD children differed from that of the non-ADHD children