Prevalence of Torque teno virus in healthy donors of Paraná State, southern Brazil

OBJECTIVE: To determine the prevalence of the Torque teno virus in healthy donors in the northern and northwestern regions of the state of Paraná, southern Brazil.METHODS: The Torque teno virus was detected by a nested polymerase chain reaction using a set of oligoprimers for the N22 region.RESULTS: The prevalence of the virus was 69% in 551 healthy blood donors in southern Brazil. There was no statistically significant difference between the presence of the virus and the variables gender, ethnicity and marital status. There was significant difference in the prevalence of the virus regarding the age of the donors (p-value = 0.024) with a higher incidence (74.7%) in 18- to 24-year-old donors.CONCLUSION: A high prevalence of Torque teno virus was observed in the population studied. Further studies are needed to elucidate the routes of contamination and the clinical implications of the virus in the healthy population.

Torque teno virus among dialysis and renal-transplant patients

Patients who undergo dialysis treatment or a renal transplant have a high risk of blood-borne viral infections, including the Torque teno virus (TTV). This study identified the presence of TTV and its genome groups in blood samples from 118 patients in dialysis and 50 renal-transplant recipients. The research was conducted in a hospital in the city of Maringá, state of Paraná. The viral DNA, obtained from whole blood, was identified by using two nested Polymerase Chain Reactions (PCR). The frequencies of TTV were 17% and 36% in dialysis patients using the methodology proposed by Nishizawa et al. (1997) and Devalle and Niel (2004), respectively, and 10% and 54% among renal-transplant patients. There was no statistically significant association between the frequency of the pathogen and the variables: gender, time in dialysis, time since transplant, blood transfusions, and the concomitant presence of hepatitis B, for either the dialysis patients or the renal-transplant recipients. Among dialysis patients and renal-transplant recipients, genogroup 5 was predominant (48% and 66% respectively), followed by genogroup 4 (37% and 48%) and genogroup 1 (23% and 25%). Genogroup 2 was present in both groups of patients. Some patients had several genogroups, but 46% of the dialysis patients and 51% of the renal-transplant recipients had only a single genogroup. This study showed a high prevalence of TTV in dialysis patients and renal-transplant recipients.

Terapia dialítica em mulheres do estado do Paraná, município de Maringá e região metropolitana / Dialysis therapy in women from Parana State, Maringa city and metropolitan region

O objetivo deste estudo foi analisar a prevalência de diálise em mulheres no estado do Paraná, município de Maringá e região metropolitana. Estudo quantitativo, descritivo, de corte transversal. Foi estudada a prevalência de diálise em mulheres no estado do Paraná, município de Maringá e região metropolitana, no período de 1999 a 2007, através do Sistema de Informações Ambulatoriais do Sistema Único de Saúde (SIA/SUS), no programa do Departamento de Informática do Sistema Único de Saúde (DATASUS).Houve aumento da taxa de prevalência de diálise em mulheres no estado do Paraná, município de Maringá e região metropolitana no período de 1999 a 2007. No estado do Paraná, houve um crescimento de 1,71 mulheres em diálise por 100.000 habitantes do sexo feminino anualmente (p≤0,05), as faixas etárias 30 a 59 anos e 60 anos e mais se revelaram como fatores de risco para realizar diálise no sexofeminino. No município de Maringá e região metropolitana, houve um crescimento de 0,88 de mulheresem diálise por 100.000 habitantes do sexo feminino anualmente (p≤0,05), a faixa etária 60 anos e mais se revelou como fator de risco para realizar diálise no sexo feminino.

The aim of this study was to analyze the prevalence of dialysis in women in the state of Paraná, Maringá and metropolitan region. It is a quantitative, descriptive and transversal cut study. We studied the prevalence of dialysis in women from Parana state, Maringa city and metropolitan region in the period1999 to 2007 through the Outpatient Information System of the Unified Health System (SIA / SUS), theprogram of the Department of Informatics Unified Health System (DATASUS). Increased prevalence ofdialysis in women from Parana state, Maringá and metropolitan region in the period 1999 to 2007. In the Paraná state, an increase of 1,71 women per 100,000 dialysis females annually (p ≤ 0.05), ages 30 to 59 years and 60 years and more were revealed as factors risk to perform dialysis in females. In Maringa and the metropolitan region, an increase of 0,88 women per 100,000 dialysis females annually (p ≤ 0.05),age 60 years and more was revealed as a risk factor to perform dialysis in females.

Chronic kidney disease: information on southern brazilian patients with kidney disease / Insuficiência renal crônica: conhecendo o paciente nefropata sulbrasileiro

The profile of patients undergoing haemodialysis in the dialysis unit of Hospital Santa Casa de Maringá, Maringá PR Brazil, is provided. A questionnaire on social and economic data and underlying diseases prior to the Chronic Kidney Disease (CKD) identified the patients' profile. The project was approved by the Ethics Committee of the institution. Eighty-three patients, with 54.21% males, were interviewed. Age bracket ranged between 20 and 59 years in 65.06% of patients. Only 27.71% maintained jobs after the diagnosis and the start of treatment; 63.86% had an average personal income between 1 and 3 minimum wages; 63.85% did not practice any physical activity. Moreover, 53.01% belonged to the European-Brazilian white group; 20.48% to the Afro-Brazilian brown group; 19.28% to the Afro-Brazilian Negro group; 6.02% to other ethnic groups. Further, 85.54% patients reported having an underlying disease prior to the CKD, namely, 61.45% were hypertensive; 31.33% were diabetics and 20.48% had other diseases. Results show the need of a greater attention to these patients' health care to reduce the negative impacts related to the chronic disease focused.

Este estudo teve como objetivo identificar o perfil dos pacientes em tratamento hemodialítico do setor de diálise do Hospital Santa Casa de Maringá - Paraná, Brasil. Para a identificação do perfil destes pacientes foi utilizado um questionário contendo questões que abrangem dados socioeconômicos e doenças de base anteriores à Insuficiência Renal Crônica (IRC). O projeto foi aprovado pelo Comitê de Ética em Pesquisa da instituição. Entre os 83 pacientes entrevistados, 54,21% eram do sexo masculino. A faixa etária variou de 20 a 59 anos para 65,06% dos pacientes. Somente 27,71% continuaram trabalhando após o diagnóstico e início do tratamento. A renda pessoal média ficou entre um e três salários mínimos para 63,86% dos indivíduos. A atividade física está ausente em 63,85%. Quanto à etnia, foi verificado que 53,01% eram brasileiros descendentes de europeus/brancos, 20,48% brasileiros afrodescendentes/pardos, 19,28% brasileiros afrodescendentes/negros e 6,02% declararam como pertencentes à outras etnias. Entre os pacientes, 85,54% declararam possuir outra doença de base anterior à IRC sendo: 61,45% hipertensão arterial, 31,33% diabetes e 20,48% outras doenças. Estes resultados indicam a necessidade de uma melhor atenção ao cuidado da saúde desses pacientes para a redução dos impactos negativos relacionados à cronicidade da doença.