ABSTRACT
Objective To evaluate the effect of clinic-pathological variables on prognosis and recurrence of the aged women suffered from borderline epithelial ovarian tumors. Methods The clinical and follow-up data of 102 cases were analyzed retrospectively. Univariate and multivariate logistic regression analysis were used to assess independent prognosis and recurrence factors.Results The postoperative accessory treatment, peritoneal implantation and lymph nodes metastasis could influence the 5-year survival rate(χ2=19.311, 11.054, 18. 559, all P＜0.01). The surgery procedure, peritoneal implantation, lymph nodes metastasis and microinvasion could influence the recurrence rate(χ2=23.606, 23.583, 25.774, 23.583, all P＜0.01). The logistic regression model showed that the postoperative accessory treatment and peritoneal implantation were the two independent prognosis factors (OR=0.060, 35.319, all P＜0.01). The surgery procedure,peritoneal implantation and microinvasion were the three independent factors affecting recurrence(OR =0.001, P＜0.05;OR=60.952, P＜0.05;OR=88.874, P＜0.01). Conclusions The early standard treatment on borderline epithelial ovarian tumors of the aged women have an excellent prognosis, the risk of recurrence remains in some patients. We emphasize that these patients with highrisk factors should be main surveillance population.
ABSTRACT
Objective:To explore the feasibility and mechanism on changing acoustic environment in tissue (AET) of rabbit liver by HL-1 intravenous injection.Methods:10 New Zealand rabbits were randomly divided into two groups,treatment and control group with 5 rabbits respectively.Before rabbit livers were ablated in vitro by using focused ultrasound(FU)(3.04W,11MHz),HL-1 was injected intravenously via rabbit ear marginal vine for 20 minutes.Rabbits were sacrificed by excessive anesthesia after 1 hour,and small pieces of liver tissue were cut for pathological exammation.Rabbits liver were ablated with FU in the manners of dot scan in different preplanned liver areas with various treatment time of 3s,6s,9s,12s and 15s,and its temperature in each dot was measured immediately after ablation.2 to 3 pieces of non-damaged tissues in each liver were chosen to measure its density after trial.All processes were the same as those of experiment group except replacing HL-1 with saline in control group.Results:Similar time-temperature curve showed in two groups except the temperature was higher in every dot in treatment group than that of control group( P
ABSTRACT
Objective:To explore the effects of ablation of normal rabbit liver tissue by combination of high intensity focused ultrasound(HIFU) and iodized oil emulsion(HIFU liposome 2,HL-2) and the grey scale changes in target region.Methods:Rabbit liver was ablated with HIFU under certain parameters one hour after HL-2 was injected intravenously in the experimental group.The grey scale in target region and the exposure time were recorded.All processes in control group were the same as those in the experimental group only HL-2 was replaced by saline.Results:The changes of grey scale in the target region were similar in two groups.Typical coagulation necrosis happened both in two groups under gross and histological examination.The energy efficiency factor (EEF)in the experimental group was less than that in the control group(P