ABSTRACT
<p><b>OBJECTIVE</b>To explore the significance of damage control surgery (DCS) in the treatments of severe pancreaticoduodenal injuries.</p><p><b>METHODS</b>Clinical data of 19 patients with severe pancreaticoduodenal injuries managed with DCS approach in Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine and the First Affiliated Hospital of Wenzhou Medical College from March 2005 to January 2013 were analyzed retrospectively.</p><p><b>RESULTS</b>Three cases were cured after damage control operation and postoperative ICU resuscitation treatment. Twelve cases underwent definite operations (distal pancreaticojejunal Roux-en-Y anastomosis, proximal duodenojejunal Roux-en-Y anastomosis or pancreaticoduodenectomy) after damage control operation and postoperative ICU resuscitation treatment and cured. Four cases died after damage control operation due to multiple organ failure and the mortality was 21.1%.</p><p><b>CONCLUSION</b>Application of DCS approach can improve the prognosis of patients with severe pancreaticoduodenal injuries.</p>