Analysis on inheritance effect of famous doctor studio based on R software and CiteSpace / 中华医学科研管理杂志

Objective:To evaluate the construction effect of famous doctor studio and the correlation among the acceptance indexes by analyzing the achievements of famous doctor studio in the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine.Methods:R software was used to count the relevant data of national famous medical studios approved from 2010 to 2018, and the advantages were analyzed by radar chart; Spearman correlation coefficient was calculated, and R software was used to draw the correlation heat map between the evaluation indexes; papers published by studio members during the construction period were retrieved, which were transformed into refworks format, imported into CiteSpace software to draw a visual knowledge map.Results:A total number of 506 articles were included in this study, involving 25 evaluation indexes and 22 national famous doctors' studios. The statistical analysis results showed that there was a significant positive correlation between the number of academic experience papers of famous and senior TCM experts published in core journals (V3) and the number of diagnosis and treatment schemes of dominant diseases (V1), and there was a significant negative correlation between 8 groups of indexes; Tinnitus, insomnia, premature ovarian failure, acupuncture and acupuncture therapy are research hotspots.Conclusions:When evaluating the construction effect of famous doctor studio, various indicators should be considered comprehensively, appropriately control of the number of members is helpful to improve the quality of talent training, and pay attention should be paid to experience exchange and thought collision during the training process.

Prevalence and associated risk factors of diabetes among ethnic Han residents in Guizhou / 中华流行病学杂志

<p><b>OBJECTIVE</b>To understand the fast plasma glucose (FPG) level and the epidemiologic characteristics of diabetes in ethnic Han residents of Guizhou province.</p><p><b>METHODS</b>The survey was conducted among the ethnic Han residents aged 20-80 years, who were selected through multi stage cluster sampling in Guizhou. Basic laboratory test, physical examination were performed for each subject.</p><p><b>RESULTS</b>A total of 2 967 subjects were surveyed. The average FPG level was 5.21 mmol/L for urban residents and 5.03 mmol/L for rural residents, (P<0.001) and the average FPG level was higher in males than in females (5.23 mmol/L vs. 5.09 mmol/L, P=0.003). The FPG level increased with age (P<0.001). In urban residents, the standardized prevalence of diabetes was 6.01% (crude prevalence: 7.45%), higher in males than in females (P<0.001) and increased with age. In rural residents, the standardized prevalence of diabetes was 3.47% (crude prevalence: 3.77%) and increased with age, but there was no sex specific difference in diabetes prevalence. The awareness rate of self diabetes status was 56.59%, the treatment rate was 84.47% and the plasma glucose control rate was 41.38%. Multiple logistic regression analysis indicated that risk factors for diabetes included being male, older than 40 years, family history of diabetes, frequent physical exercise, hypertension, high triglycerid level.</p><p><b>CONCLUSION</b>The prevalence of diabetes was high in ethnic Han residents in Guizhou, the differences in diabetes prevalence between urban area and rural area was statistical significant. More than half of the patients' FPG level had not been under control after treatment. The awareness rate of self diabetes status, the treatment rate and the control rate of diabetes should be improved.</p>

An Experimental Study on Zhuyin Capsule for the Treatment of Congestive Heart Failure / 广州中医药大学学报

【Objective】To investigate the therapeutic effect of Zhuyin Capsule(ZC)for the treatment of congestive heart failure(CHF).【Methods】Fifty SD rats were randomized into five groups: A(pseudo-operation),B(model),C(treated with hydrochlorothiazide 14.29?mg?kg~(-1)?d~(-1)),D(treated with ZC 0.26?g?kg~(-1)?d~(-1))and E(treated with ZC 0.51?g?kg~(-1)?d~(-1)).Except group A,rat models of CHF were established in other groups.Thirty-five days after the modeling,groups C,D and E were treated with corresponding drugs according to the experimental design for 2 days.Cardiac function and the pathological features of heart,liver and lung were examined.【Results】The changes in group A were as follows: heart rate became fast,blood pressure decreased,left ventricular end diastolic pressure(LVEDP)increased,the maximum rate of left ventricular pressure rise(+dp/dt_(max))decreased,ventricular cavity became enlarged and the wall was thin,and there appeared myocardial fibrosis,congested liver and edema in pulmonary alveoli,indicating the success of CHF model.High-dose ZC could relieved the above changes(P0.05).【Conclusion】ZC can decrease the preload and afterload of the heart,and reduce the pathological changes of heart,liver and lung in CHF rats,which may be one of its therapeutic mechanisms.