ABSTRACT
Objective:To observe the efficacy of rosuvastatin combined with the conventional treatment in the patients with acute cerebral infarction (ACI) and the influence on the serum levels of MMp2, vasostatin-2 and sICAM-1.Methods:Totally 136 patients with ACI were randomly divided into the routine treatment group and the rosuvastatin group with 68 ones in each .The patients in the routine treatment group were treated with the conventional treatment , and those in the rosuvastatin group were treated with rosuvastatin additionally.The treatment course was 15 days.The efficacy, adverse drug reactions and the changes of MMp 2, vasostatin-2 and sI-CAM-1 in the two groups were compared .Results:The effective rate was 92.65%in rosuvastatin group and that was 77.94%in the routine treatment group, and the difference was statistically significant (P0.05).Conclusion:Rosuvastatin used in the patients with ACI has better clinical efficacy than the routine treat-ment, which can reduce the levels of MMp 2, vasostatin-2 and sICAM-1 and is worthy of clinical promotion .
ABSTRACT
We analyzed coupling expansion process of three different structures of stainless steel (SUS-316LI) stents by using finite element method (FEM) simulation in this study. Firstly we made specific analysis and comparison between three stents of deformation and stress-strain distribution in the coupling expansion process and then we described the shortening rate, radial bounce rate, expand nonuniformity, safety factor and other biological mechanics performance of the three stents quantitatively. And finally we analyzed the influencing factors and the best structure of the three kinds of the stainless steel stent comprehensively. Through all the processes, we have verified the rationality of the finite element simulation result by using the expansion test in vitro.