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Objective To analyze the distribution characteristics of traditional Chinese medicine(TCM)syndrome types in patients with osteoporosis and the distribution differences of clinical and serological indicators in TCM syndrome types.Meth-ods A total of 69 patients with osteoporosis were collected from the Third Affiliated Hospital of Guangzhou University of Chinese Medicine and Qifu Hospital Affiliated to Jinan University.The general information,bone mineral density T value,fasting periph-eral venous blood in the morning were collected.The expression of telomerase protective factor 1(POT1),telomerase reverse transcriptase(TERT),serum 8-hydroxy-2'-deoxyguanosine(8-OHdG)and superoxide dismutase 2(SOD2)were detected by ELISA.Finally,the above data were statistically analyzed.Results There were significant differences in body weight,height,bone mineral density,POT1,TERT,and 8-OHdG among the four syndromes(P＜0.05).In terms of correlation,the relation-ship between bone mineral density and each parameter in different syndrome types was explored.The bone mineral density of qi stagnation and blood stasis syndrome was positively correlated with SOD2 value.There is a positive correlation between bone min-eral density and 8-OHdG in patients with Yin deficiency of liver and kidney.TERT was positively correlated with qi stagnation and blood stasis syndrome.Liver and kidney Yin deficiency syndrome was positively correlated with weight and bone mineral den-sity,and negatively correlated with TERT value.Weight was negatively correlated with qi and blood stasis syndrome.Conclusion In TCM syndrome differentiation of osteoporosis,there were statistical differences in weight,height,bone mineral density,ser-um POT1,TERT and 8-OHdG among Qi-stagnation and blood stasis,spleen-kidney Yang deficiency,liver-kidney Yin deficiency and Qi-blood-peace syndrome.In different syndrome types,serum SOD2 and 8-OHdG were the influencing factors of bone miner-al density.Serum TERT and 8-OHdG are the main factors affecting the dialectical classification of osteoporosis.
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Objective To observe the anesthesia and hemodynamic effect of etomidate compound remifentanyl in laparoscopic surgery.Methods From January 2016 to May 2016,160 patients with gynecologic laparoscopic surgery in the Second Hospital of Shanxi Medical University were selected and randomly divided into observation group and controlgroup according to the digital table,with 80 cases in each group.The observation group received the etomidate compound remifentanyl anesthesia,while the control group received the propofol compound remifentanyl anesthesia .the The anesthesia effect,awakening time,extubation time,pain relief time and systolic blood pressure (SBP),diastolic blood pressure (DBP),heart rate (HR) before and after extubation of the two groups were observed and recorded .Results The excellent and good rate in the observation group was 98.0％,which was significantly higher than 86.0％in the control group (χ2 =4.444,P<0.05).The waking time,extubation time,analgesic time in the observation group were shorter than those in the control group,the differences were no statistically significant (t =1.875,1.631,1.761,all P>0.05).At tracheal intubation,the SBP,DBP,HR and other indicators between the two groups had no statistically significant differences(t=1.301,1.093,1.097,all P>0.05).After induction of anesthesia,the SBP,DBP in the observation group were higher than those in the control group ,the differences were statistically significant (t=6.182,7.388,all P<0.05),but HR between the two groups had no statistically significant difference(t=1.428,P>0.05).After laparoscopic placement and tracheal extubation,the SBP and DBP in the observation group were significantly higher than those in the control group,the differences were statistically significant (t=5.781,5.028,all P<0.05),and the SBP in the observation group was higher than that in the control group after tracheal extubation (t=1.203,1.039,all P<0.05).Conclusion The anesthesia effect of etomidate compound remifentanyl is superior to propofol compound remifentanyl ,the hemodynamic parameters of SBP ,DBP,HR are more stable during the period of anesthesia ,the curative effect is clear .
ABSTRACT
Objective@#To observe the anesthesia and hemodynamic effect of etomidate compound remifentanyl in laparoscopic surgery.@*Methods@#From January 2016 to May 2016, 160 patients with gynecologic laparoscopic surgery in the Second Hospital of Shanxi Medical University were selected and randomly divided into observation group and control group according to the digital table, with 80 cases in each group.The observation group received the etomidate compound remifentanyl anesthesia, while the control group received the propofol compound remifentanyl anesthesia.the The anesthesia effect, awakening time, extubation time, pain relief time and systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) before and after extubation of the two groups were observed and recorded.@*Results@#The excellent and good rate in the observation group was 98.0%, which was significantly higher than 86.0% in the control group (χ2=4.444, P<0.05). The waking time, extubation time, analgesic time in the observation group were shorter than those in the control group, the differences were no statistically significant(t=1.875, 1.631, 1.761, all P>0.05). At tracheal intubation, the SBP, DBP, HR and other indicators between the two groups had no statistically significant differences(t=1.301, 1.093, 1.097, all P>0.05). After induction of anesthesia, the SBP, DBP in the observation group were higher than those in the control group, the differences were statistically significant(t=6.182, 7.388, all P<0.05), but HR between the two groups had no statistically significant difference(t=1.428, P>0.05). After laparoscopic placement and tracheal extubation, the SBP and DBP in the observation group were significantly higher than those in the control group, the differences were statistically significant (t=5.781, 5.028, all P<0.05), and the SBP in the observation group was higher than that in the control group after tracheal extubation(t=1.203, 1.039, all P<0.05).@*Conclusion@#The anesthesia effect of etomidate compound remifentanyl is superior to propofol compound remifentanyl, the hemodynamic parameters of SBP, DBP, HR are more stable during the period of anesthesia, the curative effect is clear.
ABSTRACT
Health-related quality of life (HRQoL) is a multidimensional concept for the comprehensive assessment of people's physical and mental health status,which plays an irreplaceable role in clinical treatment,pharmaceutics research,prevention and health care,health policy decision and health economy evaluation,etc.This paper summarizes the connotation,research status,assessment scales and influencing factors of health-related quality of life in order to provide reference to improve the research of health-related quality of life in the future.
ABSTRACT
Health-related quality of life (HRQoL) is a multidimensional concept for the comprehensive assessment of people's physical and mental health status,which plays an irreplaceable role in clinical treatment,pharmaceutics research,prevention and health care,health policy decision and health economy evaluation,etc.This paper summarizes the connotation,research status,assessment scales and influencing factors of health-related quality of life in order to provide reference to improve the research of health-related quality of life in the future.