Efficacy of Latanoprost for Refractory Angle-closure Glaucoma in Patients Whose Intraocular Pressure Failed to be Kept under Control by Common Anti-glaucoma Drugs / 中国药房

OBJECTIVE:To evaluate the efficacy of latanoprost for patients with refractory angle-closure glaucoma in whom the intraocular tension failed to be kept under control by common anti-glaucoma drugs.METHODS:A total of 23 refractory glaucoma cases(36 eyes)whose intraocular pressure(IOP)failed to be kept under control by common anti-glaucoma drugs were assigned to receive latanoprost alone or latanoprost combined with timolol or pilocarpine for 6 months.The intraocular tension,visual acuity,visual field and side-effect were observed.RESULTS:In acute primary angle-closure glaucoma group,the mean IOP was(27.13?5.21)mmHg before treatment vs.(16.21?3.45)mmHg at six months(P