Current therapeutic options and progress for colorectal liver metastases / 国际外科学杂志

The liver is a primary target organ of colorectal cancer metastases. Surgical resection is pres-ently the only approach that offers patients a substantial chance of cure. Five-year survival ranges 25% -39%. But by the time of diagnosis, only 10% -25% of patients were considered eligible for surgical directed thera-pies. New therapeutic modalities such as ablation, hepatic arterial infusion chemotherapy, neoadjuvant chem-otherapy and targeted therapy present promise for the future treatment of unresectable liver metastases. These treatments and progress in surgical therapy are reviewed in this article.