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1.
Journal of Korean Academy of Nursing Administration ; : 175-185, 2019.
Article in Korean | WPRIM | ID: wpr-764655

ABSTRACT

PURPOSE: Based on the theory of planned behavior, the purpose of this study was to investigate factors influencing entrepreneurial intention in nursing students. METHODS: Convenience sampling was used to recruit 434 participants from five nursing departments. The investigators used self-report questionnaires. The data were collected from October 25 to November 25, 2018. Data were analyzed using descriptive statistics and three-step hierarchical regression analysis. RESULTS: Attitude, subjective norm, and perceived behavior control of the theory of planned behavior, and role model showed a significant effect on entrepreneurial intention. The explanatory power of the whole model was 63%. CONCLUSION: Based on the results of this study, we propose developing a nursing entrepreneurial education model focusing on attitude, subjective norm, and perceived behavior control in the theory of planned behavior.


Subject(s)
Humans , Behavior Control , Education , Entrepreneurship , Intention , Nursing , Research Personnel , Students, Nursing
2.
Nutrition Research and Practice ; : 529-534, 2019.
Article in English | WPRIM | ID: wpr-760635

ABSTRACT

BACKGROUND/OBJECTIVES: The leaves of Moringa oleifera (MO) and Moringa stenopetala (MS) commonly grown in Ethiopia possess potential nutritional and medicinal value. The aim of this study was to evaluate the nutritional and functional characteristics of the dried leaf powder from two Moringa species to develop sustainable nutritional supplements for Ethiopians from locally grown plant sources. SUBJECTS/METHODS: Freshly harvested and air-dried MO and MS leaves were authenticated and the nutritional contents, such as protein, ash, lipids, and selected vitamins and minerals, were analyzed using standard analytical procedures. Amino acid compositions were also determined by an amino acid analyzer. Nine-week-old mice were randomly divided into four groups to investigate the anti-obesity effects of Moringa. The first group was fed a basal diet, the second group a high-fat diet, and the others were fed a high-fat diet containing 0.1% Moringa leaf powder from each species. After seven weeks, serum indices related to lipid profiles from each mouse were analyzed. RESULTS: The present study revealed high protein (28–29%) and ash (7–11%) contents. Glutamic acid, aspartic acid, proline, and leucine were the most abundantly found amino acids in both species. The predominant minerals in the leaf powder were calcium (826–1,530 mg/100 g), potassium (794–904 mg/100 g), and magnesium (286-431 mg/100 g). Pyridoxine (475.06 mg/100 g) and vitamin E (34.2 mg/100 g) were found only in MS. Niacin was found only in MO at 32.21 mg/100 g, whereas ascorbic acid was found in both species (3.89 and 6.19 mg/100 g dry weight for MO and MS, respectively). The results of the animal study showed that mice on a high-fat diet containing 0.1% MO leaf powder alleviated the elevation of cholesterol, triglycerides, and low-density lipoprotein cholesterol induced by the high fat diet. MO was more effective than MS in preventing hypercholesterolemia and fat deposition. CONCLUSIONS: The findings in this work confirmed that Moringa leaves of both MO and MS possessed high nutritional value but MO was better at preventing the harmful effects of the high-fat diet than MS.


Subject(s)
Animals , Mice , Amino Acids , Ascorbic Acid , Aspartic Acid , Calcium , Cholesterol , Diet , Diet, High-Fat , Ethiopia , Glutamic Acid , Hypercholesterolemia , Leucine , Lipoproteins , Magnesium , Mass Screening , Minerals , Miners , Moringa oleifera , Moringa , Niacin , Nutritive Value , Plants , Potassium , Proline , Pyridoxine , Triglycerides , Vitamin E , Vitamins
3.
Biomolecules & Therapeutics ; : 146-152, 2013.
Article in English | WPRIM | ID: wpr-201018

ABSTRACT

This study examined the total polyphenol content of eight wild edible plants from Ethiopia and their effect on NO production in Raw264.7 cells. Owing to its relatively high polyphenol concentration and inhibition of NO production, the methanol extract of Adansonia digitata L. leaf (MEAD) was subjected to detailed evaluation of its antioxidant and anti-inflammatory effects. Antioxidant effects were assessed by measuring free-radical-scavenging activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and oxygen-radical-absorbance capacity (ORAC) assays, while anti-inflammatory effects were assessed by measuring inducible nitric oxide synthase (iNOS) expression in lipopolysaccharide (LPS)-stimulated RAW264.7 cells. In the ORAC assay, MEAD was 10.2 times more potent than vitamin C at eliminating peroxyl radicals. In DPPH assay, MEAD also showed a strong ROS scavenging effect. MEAD significantly inhibited iNOS activity (IC50=28.6 microg/ml) of LPS-stimulated Raw264.7 cells. We also investigated the relationship between iNOS expression and nuclear factor kappa B (NF-kappaB) activation. MEAD inhibited IkappaBa degradation and NF-kappaB translocation from the cytosol to the nucleus in LPS-induced RAW264.7 cells without significant cytotoxic effects, as confirmed by MTT assay. These results suggest that MEAD inhibits anti-inflammatory iNOS expression, which might be related to the elimination of peroxyl radicals and thus the inhibition of IkappaBa-mediated NF-kappaB signal transduction.


Subject(s)
Adansonia , Antioxidants , Ascorbic Acid , Cytosol , Ethiopia , Methanol , NF-kappa B , Nitric Oxide Synthase Type II , Plants, Edible , Signal Transduction
4.
Korean Journal of Community Nutrition ; : 312-323, 2013.
Article in Korean | WPRIM | ID: wpr-154802

ABSTRACT

Variables affecting bone heath of growing children were analyzed among forty nine 10-12 year old elementary students in three rural regions of north west Chungnam area. Information on age of the parents, duration of breast feeding and birth weight were collected from the guardians of the participants and nutrient intake and diet quality were assessed by average of three-day food records of participants with the help of dietitians. Bone health status was measured by calceneal broadband ultrasound attenuation (BUA) using quantitative ultrasound (QUS). Results showed that anthropometic indexes and nutrient intake levels were not different between boys and girls. However, iron intake was significantly lower in girls than in boys. Girls after menarche showed lower intake levels for thiamin, riboflavin, pyridoxine and niacin than girls before menarche. z-scores of BMI were lower than -1 and higher than +1 showed shorter breast feeding period than others but the difference was statistically non-significant. Overall, the subjects did not consume enough s of calcium, vitamin C and folic acid. Zinc intake and BMI were the most significant factors affecting BUA by the results of backward elimination in multiple regression models. Phosphorous and beta-carotene intakes showed significant negative relation with BUA. This study showed that children living in the rural area of Chungnam need extra care to keep their health and nutrient intakes especially for the nutrients known to affect growth. Tailored nutrition education needs to be more focused on the improvement of bone health status of children.


Subject(s)
Child , Female , Humans , Ascorbic Acid , beta Carotene , Birth Weight , Breast Feeding , Calcium , Diet , Folic Acid , Iron , Menarche , Niacin , Nutritional Status , Parents , Pyridoxine , Riboflavin , Zinc
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