ABSTRACT
Objective To explore the early diagnostic value of multi b value magnetic resonance diffusion weighted imaging ( DWI) combined with dynamic enhanced scan imaging for the early diagnosis of prostate cancer . Methods The clinical data of 43 patients with prostate cancer admitted to the Fifth Affiliated Hospital of Southern Medical University from January 2015 to July 2017 were analyzed.All patients underwent routine MRI examination , including 38 cases of DWI examination ,32 cases of dynamic enhanced MRI ,and 30 cases of combined examination . The values of B were 600,800,1000s/mm2 ,and the apparent diffusion coefficient ( ADC) of the DWI high signal region and the analysis of ADC were measured .Results According to different b values , the ADC value could be calculated by drawing ROC curves.When the b value was 600s/mm2,the ADC threshold was 1.62 ×10 -3 mm2/s;when b value was 800s/mm2 ,the threshold was 0.45 ×10 -3 mm2/s;when the b value was 1000s/mm2 ,the threshold value was 1.39 ×10 -3mm2/s.When the b value was 800s/mm2,the diagnosis effect was the best for prostate cancer . The sensitivity,specificity and accuracy of multi b value DWI combined with dynamic enhanced MRI in diagnosing prostate cancer were 83.33％,96.67％ and 93.33％,respectively.Conclusion Multiple b value DWI and dynamic enhanced MRI have distinctive characteristics in the diagnosis of prostate cancer .Their combination makes up their deficiency and greatly improves the early diagnosis rate of prostate cancer .