Fertilization and Pregnancy Rate after Intracytoplasmic Sperm Injection with Spermatozoa Extracted from the Testicle Biopsy / 대한비뇨기과학회지

In case requiring microsurgical epididymal sperm aspiration(MESA) for congenital absence of the vas deferens or unreconstructable obstructive azoospermia, spermatozoa sometimes could not be retrieved from the epididymis or were necro and teratozoospermia. We studied whether testicular biopsy sperm extraction (TESE) in such cases could yield spermatozoa that would result in successful fertilization and pregnancy using intracytoplasmic sperm injection(ICSI) from November, 1994 to April, 1995. Thirty cycles were treated with TESE-ICSI. The mean age of husbands was 34 years(range 25 to 42 years). A total of 426 oocytes were collected and 333 were subsequently microinjected. Normal fertilization occurred in 234 oocytes(70.3%). Thirty cases underwent embryo transfer, with a total of 176 embryos(75.2%) transferred. Twelve cases conceived with a clinical pregnancy rate of 40. O% per transfer and all of whom are ongoing normal pregnancy. Conclusively, when epididymal spermatozoa can not be retrieved TESE Would be final resort that is also very effective with most patients obtaining high fertilization and pregnancy rates. It appears that all cases of obstructive azoospermia can now be successfully treated.

Urodynamic Findings in Genuine Stress Incontinence / 대한비뇨기과학회지

From October 1990 through July 1991, 187 women who complained of urinary incontinence underwent investigation in the department of urology, especially urodynamically, compared with 42 women with female urethral syndrome as control group. The following results were obtained ; mean functional urethral length was 3.1+/-0.9cm and mean maximal urethral closure pressure was 80.2+/-2.4cmH2O in genuine stress incontinence patients. But each results of female urethral syndrome were 3.6+/-0.7cm and 121.1+/-3.8cmH2O, respectively, and were higher than those of genuine stress incontinence (p <0.05 ). The incidence of positive pressure equalization of genuine stress incontinence was higher than that of control group, as 85.6% and 14.3% (p<0.05). The findings of uroflowmetry and cystometry showed within normal limits in genuine stress incontinence and poor voiding pattern in female urethral syndrome. Conclusively. urodynamic study was important for diagnosis and follow up of genuine stress incontinence.