ABSTRACT
A neurofibroma is a benign tumor of the peripheral nerve sheath characterized by proliferation of Schwann cells, perineural cells, and endoneurial fibroblasts. Different types of neurofibromas can be identified, including localized, plexiform, and diffuse types. Neurofibromas can involve any site on the body skin. The diffuse variant is rare and occurs primarily in children and young adults. It involves the skin and subcutaneous tissue in a plaque-like fashion on the head and neck regions. We present a case of a 10-year-old boy who had a diffuse neurofibroma on the scalp.
Subject(s)
Child , Humans , Young Adult , Fibroblasts , Head , Neck , Neurofibroma , Peripheral Nerves , Scalp , Schwann Cells , Skin , Subcutaneous TissueABSTRACT
Warts are benign proliferations caused by human papillomavirus (HPV) that commonly involve the skin and other epithelial tissues. Many therapeutic modalities are available for the treatment of warts. We report 2 cases of doughnut-shaped warts following cryosurgery with liquid nitrogen. Our cases demonstrate that, after removal, relapse of warts within a few weeks is frequent and probably due to sub-clinical or latent HPV infections surrounding the warts. Our cases suggest that we should be aware of possible recurrence and that adjuvant therapy, such as immune response modifiers with potent antiviral activities, should be used to reduce the incidence of wart recurrence after cryosurgery.
Subject(s)
Humans , Cryosurgery , Incidence , Nitrogen , Recurrence , Skin , WartsABSTRACT
No abstract available.