ABSTRACT
Objective To understand the production condition of Chinese medicinal materials in Dingxi City during 2004-2014 from the aspects of planting area, yield of per unit area and total product; To provide technical guidance for future research on Chinese medicinal materials in Dingxi City. Methods Statistics like planting area, yield of per unit area and total product in counties (districts) collected by Dingxi Municipal Statistics Department were adopted for analysis. Results During 2004-2014, planting area of Chinese medicinal materials in Dingxi City reflected an upward trend, and Minxian County had the largest planting area, followed by Longxi County, Weiyuan County. Lintiao County showed the most obvious increase in planting area, followed by Zhang County. Planting area in Anding County and Tongwei County reflected a downward trend. Minxian County has the highest average per unit area yield of Chinese medicinal materials, as the 3.10 t/hm2. Total product of Chinese medicinal materials in Dingxi City showed great changes, and decreased in Anding County. Conclusion Conclusion During 2004-2014, the planting area, yield of per unit area and total product of Chinese medicinal materials showed an upward trend in general and differences in different counties (districts).
ABSTRACT
Objective By learning about the current basic situation of research on national scientific and technological achievements of three species of Chinese herbal, Radix Angelicas, Radix Astragall and Radix Codonopsis, to reveal the features in literature and research content, and provide reference for related research in future. Methods By using content analysis approach, the basic situation of achievements, the research content of achievements, and assessment and application of achievements were classified and statistically analyzed by classifying and statistical function of computer. Results The provinces that rank the top of national scientific and technological achievements of the three species of Chinese herbal were Gansu, Hebei and Shandong. The achievements were mainly undertaken by college or university, hospital and scientific research institutions. The source of project achievements mainly originated from local project and optional project. The research content of the achievements largely focused on the fields like drug therapeutic effect, pharmaceutical preparation, cultivation techniques, storing and processing. Conclusion In the database (HowNet) of national scientific and technological achievements, the amplification of national scientific and technological achievements of the three species of Chinese herbal is slow, the achievements mainly focus on application technology, the conversion rate of achievements is low, and large amount of data of achievement items in database is missing.
ABSTRACT
Objective To investigate the effectiveness and safety of combined heparin and acutobin in the treatment of acute inferior vena cava thrombus in rabbits. Methods The inferior vena cava thrombus model was established in 72 rabbits and they were randomly divided into three groups; heparin group(A) , group for combination of urokinase and heparin (B), group for combination of acutobin and heparin (C) ,each group including 24 rabbits. Drugs were administrated 3 days after thrombosis. Coagulation indexes were tested to assess their safety, and Doppler ultrasound was used to assess their effectiveness, on day 3, day 7, and day 10. Results The prolongation of prothrombin time ( PT) in group C was shorter than that in group B( P < 0. 05 ) , the fibrinogen ( FBG) value in group C was lower than that in group B (P < 0. 05 ) , the prolongation of PT in group B and group C was longer than that in group A (P < 0. 01), the FBG value of group B and C were higher than that in group A ( P < 0. 01 ), D-dimer ( D-D) value in group B and C gradually returned to normal range. There was no difference between the two groups (P > 0. 05). The thrombolytic effect in group B and C were better than that in group A, statistical difference was reached between groups B and A (P <0. 01), and the difference was statistically significant between groups C and A 10 days after administration (P < 0. 01). Thrombolytic effect was not different statistically between groups B and C (P > 0. 05). Conclusion Acutobin combined with heparin in the treatment of acute inferior vena cava thrombus in rabbits was effective and safe.