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Chinese Journal of Contemporary Pediatrics ; (12): 596-600, 2014.
Article in Chinese | WPRIM | ID: wpr-254241

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the survival rate, complications during hospitalization, and prognostic factors in extremely preterm infants (gestational age less than 28 weeks) in the neonatal intensive care unit (NICU).</p><p><b>METHODS</b>A retrospective analysis was performed on 90 extremely preterm infants who were admitted to the NICU between January 2011 and March 2013 to investigate the perinatal data, delivery and resuscitation, ventilation/oxygen supply during hospitalization, mortality, and the incidence of severe (grade III/IV) intraventricular hemorrhage (IVH), bronchopulmonary dysplasia (BPD), retinopathy of prematurity (ROP), patent ductus arteriosus (PDA), and septicemia.</p><p><b>RESULTS</b>Among the 90 extremely preterm infants, the gestational age, birth weight, overall survival rate, mortality, and withdrawal rate were 26±1 weeks, 898±165 g, 57%, 9%, and 34%, respectively. The incidence rates of neonatal respiratory distress syndrome, BPD, PDA, ROP, and grade III/IV IVH were 88%, 85%, 69%, 68%, and 31%, respectively. The surviving infants had a mean length of hospital stay of 83±18 days and a mean weight at discharge of 2 419±300 g. The multivariate logistic regression analysis showed that grade III/IV IVH and pulmonary hemorrhage were high-risk factors for death or withdrawal, while antenatal corticosteroids were the protective factor for outcome (P<0.05).</p><p><b>CONCLUSIONS</b>The survival rate of extremely preterm infants is still much lower than that in developed countries. grade III/IV IVH, and pulmonary hemorrhage are important prognostic factors.</p>


Subject(s)
Female , Humans , Infant, Newborn , Male , Bronchopulmonary Dysplasia , Epidemiology , Ductus Arteriosus, Patent , Epidemiology , Infant Mortality , Infant, Extremely Premature , Logistic Models , Prognosis , Respiratory Distress Syndrome, Newborn , Epidemiology , Retinopathy of Prematurity , Epidemiology , Retrospective Studies , Survival Rate
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