ABSTRACT
OBJECTIVE: To observe the effects of combined treatment using salmeterol / fluticasone propionate and lip shrinkage respiration on the treatment of patients with pneumoconiosis complicated with chronic obstructive pulmonary disease( COPD). METHODS: By random number table method,98 patients with stable pneumoconiosis complicated with COPD were divided into 3 groups: drug treatment group( 33 cases) was treated only with inhalation of salmeterol /fluticasone propionate( 50 μg /500 μg),twice a day; lip shrinkage respiration group( 34 cases) was treated with abdominal breathing and lip shrinkage respiration training,three times daily for 15 min per session; combined treatment group( 31 cases) was treated with both the above treatments. Before and after 6 months of treatment,the lung function,the 6-minute walk distance and the oxygen saturation( Sa O2) were detected. The modified Medical Research Council( m MRC) Respiratory Questionnaire was used to evaluate the degree of dyspnea. RESULTS: After 6 months of treatment,the forced vital capacity percentage( FVC%),percentage of forced expiratory volume in one second( FEV1%),maximum ventilatory volume( MVV),6-minute walking distance,m MRC degree and the Sa O2 improved in the patients of these 3groups compared with those before treatment( P < 0. 05). Compared with the drug treatment group or lip shrinkage respiration group after treatment,the FVC%,FEV1%,MVV,6-minute walking distance and the Sa O2 in the combined treatment group were higher( P < 0. 05),and the m MRC degree was lower( P < 0. 05). CONCLUSION: Salmeterol /fluticasone propionate combined with lip shrinkage respiration treatment had better therapeutic effect than single treatment in treating patients with pneumoconiosis combined with COPD.
ABSTRACT
Objective: To discuss the clinical features and treatment of intracranial hemangiopericytoma (HPC). Methods: The medical records including clinical features, imaging features, pathological results and treatment methods in 31 patients with HPC were reviewed retrospectively. To compare the difference in progression-free survival (PFS) among patients receiving different treatments. Results: Thirty-one patients with initial HPC were treated with operation and radiation. Gross total removal (GTR) was achieved in 16 patients, followed by postoperative adjuvant fractionated external beam radiation therapy (EBRT). Of 15 patients with subtotal removal (STR), 6 patients accepted EBRT, and 9 patients were treated with adjuvant gamma knife surgery (GKS). The median PFS of patients with GTR (89 months, 64-126 months) was longer than that of patients with STR (49 months, 26-81 months) (P 0.05). Conclusion: GTR followed by adjuvant radiation provides patients with a better outcome. Copyright © 2014 by TUMOR.