ABSTRACT
Objective To investigate clinical observation of different narcotic drugs compatibility in elderly patients with laparoscopic resection of tumor .Methods From June 2015 to June 2017 ,86 cases of elderly lapa-roscopic tumor resection were selected from our hospital .They were divided into the observation group and the control group according to the random number table ,each with 43 cases .The control group received propofol and dexmedetomidine anesthesia ,and the observation group received sevoflurane and dexmedetomidine anes-thesia maintenance .Results The observation group anesthesia total satisfaction rate (97 .67%) higher than that of the control group (79 .07%) ,the difference was statistically significant (P＜0 .05) ;The two group af-ter 3 h and 24 h OAAS score increased after operation ,the difference was statistically significant (P＜0 .05) ;The patients in the observation group 3 h and 24 h OAAS were higher than those of the control group ,the difference was statistically significant (P＜0 .05) ;The observation group extubation time ,called the open time and the recovery time of spontaneous breathing faster than the control group ,the difference was statistically significant (P＜0 .05) ;Two group T1 time HR MAP compared with T0 time reduction ,the difference was sta-tistically significant (P＜0 .05) ;The control group at T2 of HR and T0 of MAP were constantly reduced ,the difference was statistically significant (P＜0 .05) ,while the observation group at T2 HR and MAP did not change significantly compared with T0 time ,the difference was not statistically significant (P＞0 .05) ;Two group T0 ,T1 and T2 HR ,MAP and SpO2time was not statistically significant (P＞0 .05) ;The observation group T1 and T2 HR ,MAP times higher than that of the control group ,the difference was statistically signifi-cant(P＜0 .05) .Conclusion Sevoflurane combined with dexmedetomidine combined anesthesia in elderly pa- tients with laparoscopic resection surgery is obviously good effect ,little influence on sedation ,patients with HR ,MAP and SpO2.
ABSTRACT
Objective To investigate the effect of low dose Dexmedetomidine on gastrointestinal reaction after minimally invasive surgery for cervical cancer. Methods 94 patients with cervical cancer treated with minimally invasive surgery from February 2014 to September 2016 were selected. According to the random number table method, the patients were divided into observation group (low-dose Dexmedetomidine) and control group (saline). The incidence of nausea and vomiting, the motilin level were compared between the two groups. Results The observation group was 47 cases, grade Ⅱ nausea in 7 cases, grade Ⅲ nausea in 2 cases, the total incidence was 19.15%; 47 cases in the control group, 11 cases of grade Ⅱ nausea, grade Ⅳ nausea in 4 cases, grade 2 nausea in 2 cases, the rate was 36.17%, the difference was statistically significant (P 0.05). At 6 h, 12 h and 24 h after operation, the levels of motilin in the observation group were significantly lower than those in the control group, the difference was statistically significant (P < 0.05). Conclusion Low dose Dexmedetomidine can effectively prevent and alleviate the gastrointestinal reaction after minimally invasive surgery for cervical cancer, and avoid the excessive release of motilin, worthy of clinical promoting.