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Objective To investigate the expression of GR? mRNA in the peripheral blood mononuclear cells (PBMCs) of SLE patients and analyze the relationship between GR? and immune parameters, SLEDAI score, in order to reveal the role of GR? in the pathogenesis of SLE. Methods Applying reverse transcription-polymerase chain reaction(RT-PCR) technique to semiquantitatively analyze GR? mRNA expression in SLE patients and healthy volunteer individuals. The relationship between GR? and ANA, anti-ds-DNA antibodies, SLEDAI score was analyzed. Results The expression of GR? mRNA in SLE was significantly lower than that of control group (P
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Objective To research the imaging classification and dynamic changing of bronchioloalveolar carcinoma (BAC). Methods The imaging types of BAC proved by operation and pathology in 32 cases were divided into single nodules, single segment or lobe consolidation, multiple segments or lobar consolidation and multiple diffuse nodules according to the features of plain chest films and CT at first examination. The spreading lesions in lung were recorded.The developing course and changes in size of lesions on the followed-up plain films and CT were observed, then the developing rules of different types of BAC were analyzed. Results The single noduli were enlarged and became poor defined opague shadows gradually. The single segment or lobar consolidation enlarged until the whole lobe. All single lesions progressed and coexisted with diffused nodular or opaque pulmonary involvement eventually. Multiple segments or lobar consolidation developed from peripheral to center of the segment or lobar, diffused pneumonia-like shadows appeared simultaneous. Multiple extensive nodules showed a trend of getting larger and then fused.Conclusion Different types of BAC have theirown developing rule,but they finally form a consequence that the primary lesion coexisted with the spread ones from different way.
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Objective To improve the diagnostic quality of tumors composed of smooth muscles in alimentary tract.Methods The clinical and X-ray date of 40 cases of smooth musles tumors confirmed by surgery and pathological examination.Results Fifteen cases in the esophagus (including leiomyoma 14,leiomyosarcoma 1)showed the following X-ray appearence:filling defect,unfolding of mucous membrane,widening of the canal and pericanal mass 25 cases in the stomach and intestine(including leiomyoma 6,leiomyoplastoma 7,leiomyosarcoma 12)showed the following X-ray changes depending on the way of tumor,grows,cyst formation caused by tumor necrosis,compression of the stomach or intestine and adjacent organs,rarely seen calcification in tumor.The X-ray changes of small intermascular leiomyoma were short of specific X-ray signs.Conclusion X-ray exeamination is a reliable diagnostic method for smooth muscles tumors in alimentary tract.