ABSTRACT
Objective To explore the situation and the impact of early postnatal sucking and health educa-tion on early maternal lactation physical rehabilitation of primipara.Methods 100 primiparas were randomly divided into two groups,50 cases in each group.The control group received routine care,the observation group was given suck and health care education on the basis of the control group.The maternal lactation and physical rehabilitation was compared between the two groups.Results The good rate of the maternal health knowledge in the observation group was 92.00%,the good rate of ability of nursing master was 86.00%,the lactation time was (16.46 ±2.43)h,which were significantly better than the control group(χ2 =14.03,14.89,t =10.22,all P <0.05).The postpartum rehabil-itations of the observation group were better than those of the control group(t =3.86,4.42,4.68,5.67,677,5.46, 571,4.27,3.98,508,all P <0.05).The incidence rate of complication of the observation group was 6.00%,which was significantly lower than 22.00% of the control group(χ2 =5.24,P <0.05).Conclusion First mothers receive early postnatal sucking and health education can increase their milk production capacity,promote physical rehabilitation.
ABSTRACT
Background and purpose:Advanced pancreatic cancer is characteristic of poor treatment eff icacy and short survival time. Gemcitabine is considered as front-line therapy for advanced pancreatic cancer. Gemcitabine combinations have shown a favorable impact on survival. We compared gemcitabine-based combination cheme therapy and gemcitabine(GEM) alone in patients with advanced pancreatic cancer through Meta analysis in phase Ⅲ clinical trials. Methods:MEDLINE and EMBASE searches were supplemented by information from trial registers of phase Ⅲ randomized controlled trials(RCTs) for GEM-based combination therapy and GEM alone for advanced pancreatic cancer. A quantitative meta-analysis was carried out by two reviewers based on the inclusion criteria from all available RCTs. The Meta-analysis involved 6-months and 1-year survival rate and objective remission rate(ORR) . Results:The Meta-analysis included 20 RCTs. The result of our Meta-analysis showed that there was signifi cant improvement in the GEM combination group with regard to the 1-year survival rate(RR:0.87,95%:(0.78,0.96) ,P=0.008) . The other result of our meta-analysis showed no signifi cant difference between two groups. Conclusion:GEM-based combination therapy may be effective with regard to the survival rate compared with GEM alone.