ABSTRACT
【Objective】 To explore the deferral causes of apheresis platelet donors during primary screening in Qinghai, so as to take appropriate measures to improve the pass rate of donors. 【Methods】 The primary screening results of 6 673 apheresis donors from January 2018 to January 2020 in Qinghai were analyzed retrospectively. And the deferral results of donors were compared according to high(>2 500 m), middle(about 2 000 m) and low(<1500 m) altitude. 【Results】 41.7%(531) of those high-altitude blood donors were deferred, as low Plt accounted for 13.2%(168), high ALT 11.9%(151), high Hct/Hb/RBC 11.8%(150), and limepic blood 4.0%(51). 8.1% of the middle-altitude donors were deferred. As for low-altitude donors, low HCT, Hb and RBC(0.6%, 8 cases) were the dominant reason. 【Conclusion】 The different altitudes and living habits of blood donors may result in their deferral. Appropriate measures should be carried out for apheresis donors from areas of different altitudes when recruiting donors, so as to elevate the pass rate.
ABSTRACT
Objective To identify the clinical characteristics of pediatric antiphospholipid syndrome (APS) patients with pulmonary embolism.Methods The clinical data of 18 children with APS combined with pulmonary embolism treated in our department from January 2007 to January 2017 were retrospectively analyzed.The clinical and immunological indexes of the APS patients with pulmonary embolism were summarized.Results 18 patients (among whom 9 cases were primary APS and the other 9 cases were secondary APS) had pulmonary embolism and all of them were non-shock type,which was the first presenting manifestation in 9 cases of them.15 patients suffered from deep vein thrombosis at the same time,mainly in lower extremities.2 patients had thrombotic recurrence in primary APS.Primary APS was more often seen in males (7/9 vs 1/9,x2 =28.033) and much yonger [(12.3 ± 1.1) years vs (16.5 ± 1.2) years,t =5.361] than those with secondary APS,with statistically significant differences (P ≤ 0.05).Conclusions Pulmonary embolism can be the first symptom in prediatric APS patients and all of them are non-shock type.A majority of them suffer from deep vein thrombosis in the lower extremities.Positive anti-nuclear antibodies can be seen in primary APS patients,but there is no significant difference between primary APS and secondary APS about the clinical and immunological indexes.