ABSTRACT
Objective To investigate the effect of Q laser on microcirculation structure and skin barrier function of subcutaneous tissue in patients with pigmented dermatosis.Methods The Q laser was used in treatment of 100 cases of pigmented skin diseases,and the skin barrier function was detected before and after treatment in patients with lesions,including sebum content,transepidermal water loss of skin moisture;difference of skin barrier function in patients was analyzed before and after treatment;the structural change of microcirculation were observed before and after treatment of skin tissue;the clinical curative effects of patients after treatment were analyzed,and then the patients were followed up to evaluate the recurrence rate.Results After the treatment of patients with skin lesions,barrier function was compared with a significant difference.Compared with before treatment,rise,oil content of skin lesions in patients with skin moisture content,transepidermal water loss of skin moisture of the patient improved obviously after treatment.The effective rate was 94 ％ in the 100 cases of skin diseases.No hypopigmentation or scar occurred in the patients.And the follow-up showed that the recurrence rate was relatively low.Conclusions Adjusted Q laser may participate in the improvement of microcirculatory disturbances through special mechanisms,so as to regulate the skin barrier function of patients.