ABSTRACT
Currently hypothermia neuroprotection is one of the study topics of general interest. The studies of therapeutic hypothermia for acute stroke are increasingly arousing general concern. This article reviews the mechanism of therapeutic hypothermia for acute stroke, the effect of increased body temperature on acute stroke, and the clinical application of therapeutic hypothermia for acute stroke.
ABSTRACT
Objective To research the clinical significance of leukocyte-platelet aggregates(PLA)in patients with acute cerebral infarction.Methods Sixty-five patients with acute cerebral infarction and 24 controls.The levels of PLA,platelet-neutrophil aggregates(PNA),platelet-lymphocyte aggregates(PLyA)and platelet-monocyte aggregate(PMA)were analyzed by two-color flow cytometry,soluble P-selectin(sP-sel)was detected by ELISA,serum C-reaction protein(CRP)was detected by nephelometry and platelet aggregation rate(PAR)was measured by blood agglutination.Results There were no differences in the percentages of PLA,PNA and PLyA between patients(4.12?1.17%,4.09?1.27%,4.28?1.09%)and controls(4.10?0.99%,3.98?1.12%,4.01?1.98%).However,in the patients before treatment,the percentage of PMA(11.54?1.88%)was significantly increased compared with that after treatment(8.40?2.74%,P
ABSTRACT
Objective To investigate the changes of platelet-leukocyte aggregations(PLA) in patients with acute cerebral infarction and its relationship with C-reactive protein(CRP) and platelet aggregation rate(PAgT).Methods The PLA,CRP and PAgT were measured in 46 patients with acute cerebral infarction(CI group) and in 24 patients without cerebral vascular diseases(control group).Results The platelet-monocyte aggregations(PMA),PAgT and CRP in CI group were((13.00?0.76)%,(59.46?3.07)%,(9.39?1.28) mg/L,respectively,however,there were(6.55?0.29)%,(39.38?5.42)%,(2.37?0.46)mg/L respectively in control group.There were significant differences between the two groups(all(P