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Objective@#To analyze the risk factors for lung cancer and to provide scientific evidence for prevention of lung cancer.@*Methods@#A total of 461 newly diagnosed patients with primary lung cancer from January 2015 to June 2017 in Shaoxing were selected as the case group. Six hundred healthy residents with the same residence,distribution of gender and age as the cases were selected as the control group by frequency matching method. A questionnaire survey was conducted to collect demographic characteristics,family history of major chronic diseases,disease history and behavioral factors. The method of case-control study and multivariate logistic regression model were used for statistical analysis of the risk factors for lung cancer.@*Results@# The results of multivariate logistic regression analysis showed that after adjusting for age and gender,family history of cancer（OR=6.606,95%CI：3.439-12.689）,history of lung diseases（OR=2.836,95%CI：1.208-6.659）,high level of stress（OR=2.485,95%CI：1.830-3.376）,low consumption of fresh vegetables（OR=3.116,95%CI：2.470-3.930）and smoking（OR=6.029,95%CI：3.716-9.783）were risk factors for lung cancer;after adjusting for age,gender,family history of cancer,history of lung diseases,stress levels and consumption of fresh vegetables,quitting smoking for less than ten years was a risk factor for lung cancer（OR=4.751,95%CI：2.404-9.386）compared with quitting smoking for ten years or above.@*Conclusion@#Family history of cancer,history of lung diseases,high level of stress,low consumption of fresh vegetables and smoking were risk factors for lung cancer.
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Objective To analyze the detection rate of lung cancer during 2009-2013 in Shaoxing of Zhejiang province and its time trend. Methods The data of lung cancer in Shaoxing from 2009 to 2013 with a total coverage population of 21 970 825 person-year (male 10 993 657 person-year, female 10 977 168 person-year), was collected to calculate the detection rate, age adjusted detection rate, percentage change of incidence (PC), etc. The annual percentage change (APC) of incidence was estimated by linear regression based on the logarithm of the incidence rates observed. Results During 2009-2013, a total of 9 973 new cases were diagnosed as lung cancer with the sex ratio of male to female being 2.44∶1. The detection rate of lung cancer was 45.39/100 000 (male 64.35/100 000, female 26.41/100 000), age-standardized detection rate by Chinese standard population (ASR China) was 20.09/100 000 (male 28.37/100 000, female 11.66/100 000), age-standardized detection rate by world standard population (ASR world) was 27.26/100 000 (male 37.83/100 000, female 15.73/100 000). The cumulative rate and truncated rate of those aged 0-74 and 35-64 were 3.40% (male 4.80%, female 1.91%) and 39.90/100 000 (male 54.44/100 000, female 24.81/100 000). The detection rate of lung cancer increased from 34.29/100 000 in 2009 to 59.91/100 000 (APC=13.88%, P=0.006<0.05), among males the detection rate increased from 50.60/100 000 to 82.91/100 000 (APC=12.52%, P=0.011<0.05), and the female detection rate increased from 17.81/100 000 to 36.78/100 000 (APC=17.70%, P=0.005<0.05). In Shaoxing, the detection rate of lung cancer increased obviously among the residents over 45 years of age. For each age group except 15-and 20-, the male detection rate was higher than the female incidence. Conclusion The men who were 45 years and older were at a higher risk of lung cancer in Shaoxing. The detection rate of lung cancer increased year by year from 2009 to 2013 in Shaoxing, especially among women over 65 years of age.
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Objective To analyze the detection rate of thyroid cancer from 2009 to 2013 in Shaoxing of Zhejiang province and its time trend.Methods The data of thvroid cancer in Shaoxing from 2009 to 2013 was collected to calculate the detection rate,age adjusted detection rate and percentage change of incidence,and the annual percentage change (APC) of incidence was estimated by linear regression based on the logarithm of the incidence rates observed.Results lDuring 2009-2013,a total of 3 290 new cases were diagnosed as thyroid cancer with the sex ratio of male to female being 1 ∶ 3.69.The detection rate of thyroid cancer was 14.98/100 000 (male 6.39/100 000,female 23.59/100 000),with age-standardized detection rate by Chinese standard population (ASR China)9.13/100 000(male 3.94/100 000,female 14.31/100 000),and age-standardized detection rate by world standard population(ASR worll) 10.39/100 000(male 4.47/100 000,female 16.32/100 000).The detection rate of thyroid cancer increased from 7.26/100 000 in 2009 to 27.26/100 000 (APC =39.65％,P＜0.05),with the detection rate among males increasing from 2.42/100 000 to 12.65/100 000(APC =48.44％,P＜0.05),and the detection rate among female increasing from 12.15/100 000 to 41.96/100 000(APC =37.58c％,P＜0.05).In Shaoxing,most of the new thyroid cancer cases were from 25 to 59 years old,and the highest incidence happened in the group of 50-54 years.For each age group,the detection rate in female was almost over two-folls higher than the incidence in male.Conclusion The detection rate of thyroid cancer was increased year by year from 2009 to 2013 in Shaoxing,especially among the young and middle-aged women.The corresponding measures must be taken to control the risk factors of thyroid cancer.
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Objective To understand the prevalence of negative life events and its association with depressive, anxiety symptoms and dissatisfaction of school life among middle school students in Shaoxing, and to provide scientific evidence for further interventions. Methods A total number of 3 197 students (including 1 134 urban and 2 063 town adolescents) were recruited from 2 middle schools in Shaoxing, their average age was (13.73 ± 1.03) years. The Multidimensional Life Events Rating Questionnaire for Middle School Students (MLERQ), Depression Self-rating Scale for Children (DSRSC) and Screening for Child Anxiety Related Emotional Disorders (SCARED) were used to assess the mental health status, while the school life satisfaction was evaluated by the School Life Satisfaction Rating Questionnaire for Adolescents (SLSRQA), and the data were analyzed by descriptive statistics and multivariate logistic regression models. Results The prevalence of the negative life events was 84.9%, unsatisfactory examination performance (48.6%), unreached the teacher's expectation (46.2%), parental chatter (41.4%), unbalanced learning (37.9%), and getting parents scold (27.6%) constituted the main negative life events. The prevalence of depressive symptom, anxiety symptom, and dissatisfaction of school life were significantly higher among middle school students living with negative life events (41.1%, 22.6%, 26.0%) than those without negative life events (20.9%, 3.5%, 16.5%), (?2=71.33, 94.78, 19.83, P<0.001). The prevalence of the psychosomatic health involvement significantly increased with the increase of the number of the dimensions and events (P<0.001). The multivariate logistic regression showed that negative life events were the risk factors of depression, anxiety and dissatisfaction of school life. Their OR values were 2.483 (1.951-3.160), 7.245 (4.411-11.899) and 1.733 (1.325-2.267), respectively. The risk of occurring mental symptoms among children with the number of dimensions≥4 and/or the number of events≥12 was two times higher than those of children without such increase in numbers of dimensions and events. Conclusion The status of negative life events is serious among middle school students in Shaoxing. There are statistical associations between negative life events and mental symptoms.
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Objective To understand the prevalence of physical activity deficiency and its association with depressive, anxiety symptoms and dissatisfaction of school life among adolescents in Shaoxing, Zhejiang province. Method A total of 3 397 valid questionnaires from adolescents from 80 classes of 2 middle schools (including 1 420 urban and 1 977 town adolescents) were investigated for the study, their average age was (13.73±1.01) years. The Depression Self-rating Scale for Children (DSRSC) and Screen for Child Anxiety Related Emotional Disorders (SCARED) were used to assess the mental health status, while the dissatisfaction of school life was evaluated by the School Life Satisfaction Rating Questionnaire for Adolescent (SLRQA), and the data were analyzed by descriptive statistics and multivariate logistic regression models. Result The self-reported proportion of 3 397 adolescents with physical activity deficiency reached 78.5%, and the prevalence rate of depressive, anxiety symptoms and school life dissatisfaction were 55.2%, 18.9% and 31.1%, respectively. Adjusting on other potential confounders, the result of multivariate logistic regression showed that girls engaged in less physical activities, the OR value (95%CI) was 1.597 (1.348-1.892), while the adolescents with town census register and adolescents having six or more close friends participated in more physical activities, their OR values were 0.785 (0.661-0.931) and 0.565 (0.355-0.900), and insufficient physical activity was positively associated with depressive, anxiety and dissatisfaction of their school lives, their OR values were respectively 1.783 (1.506-2.105), 2.141 (1.664-2.755) and 1.337 (1.101-1.621). Conclusion High prevalence of physical activity deficiency appeared among adolescents in Shaoxing and was closely related to the presence of depressive, anxiety symptoms and school life dissatisfaction.
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Objective To analyze the incidence of malignant tumor in Shaoxing of Zhejiang Province in 2012.Methods Descriptive analysis was carried out based on our chronic disease monitoring information management system.Age-standardized incidence was calculated according to Chinese standard population in 1982 and the Segi's world population.Results The crude incidence of malignant tumor was 291.34/100 000,age-standardized rate by Chinese standard population (ASR China) and by world population was 137.29/100 000 or 176.72/100 000,respectively.The cumulative rate of the 0-74 years old group was 20.27％ and the cut rate of the 35-64 years old group was 301.49/100 000.Male crude incidence of cancer and ASR China were 330.46/100 000 and 149.28/100 000,respectively; for female,the figure was 251.93/ 100 000 and 124.79/100 000,respectively.The crude incidence and ASR China were 364.85/100 000 and 171.77/100 000 in urban area residents,and 277.86/100 000 and 130.93/100 000 for those living in rural areas.Age-specific incidence of the 0-29 years old group remained low,although the incidence was increased after 30 years old and reached the peak in the 80-84 years old group.The most common malignancy were lung cancer,gastric cancer,colorectal cancer,liver cancer,breast cancer,thyroid cancer,esophageal cancer,pancreatic cancer,cervical cancer and leukemia (76.77％).Conclusions Lung cancer,gastrointestinal cancer and female reproductive system cancer were most common malignancy in Shaoxing of Zhejiang Province in 2012.The incidence of thyroid cancer,leukemia and brain tumor is significantly increased over the past few years,which may need effective control and prevention strategies.