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Journal of the Korean Pediatric Society ; : 280-284, 1995.
Article in Korean | WPRIM | ID: wpr-49410

ABSTRACT

Iron overload from repeated blood transfusions in patients with hematologic problems is a problem of clinical significance, because eventually it can lead to secondary hemochromatosis with diabetes. So it is important to diagnose iron overload early and to restrict blood transfusions in these patients. Recently, we experienced one case of secondary hemochromatosis with diabetes in patient wi th congenital pure red cell anemia, diagnosed by serum ferritin level, TIBC, transferrin saturation, random blood sugar, C-peptide and insulin level. This patient had received 30,000ml of RBCs for 9 years. Treatments with insulin mixed spitting therapy because of insulin dependent diabetes clinically, restriction of blood transfusion and steroid therapy for maintenance of Hemoglobin level were done just after discharge. We report this one case with a brief review of the literature.


Subject(s)
Humans , Anemia, Diamond-Blackfan , Blood Glucose , Blood Transfusion , C-Peptide , Diabetes Mellitus , Ferritins , Hemochromatosis , Insulin , Iron Overload , Transferrin
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