ABSTRACT
<p><b>OBJECTIVE</b>To compare the quality of Flos Lonicerae between different producing areas.</p><p><b>METHOD</b>ICP-AES, UV and HPLC were used to determine the contents of trace elements, chlorogenic acid, total flavonoids, five iridoid glucosides, hederagenin, and oleanolic acid. SAS software system was used to perform data and cluster analyses.</p><p><b>RESULT</b>The results showed that the geo-authentic crude drug was lower in the contents of Cr and Pb but higher in the contents of chlorogenic acid, total flavonoids, five iridoid glucosides, hederagenin, and oleanolic acid than the non-authentic crude drug.</p><p><b>CONCLUSION</b>The geo-authentic crude drug of Flos Lonicerae is better in quality than the non-authentic crude drug based on the modern chemical analyses, which confirms the validity of traditional geo-based classification.</p>
Subject(s)
China , Chlorogenic Acid , Chromium , Cluster Analysis , Ecosystem , Flavonoids , Flowers , Chemistry , Lead , Lonicera , Chemistry , Oleanolic Acid , Plants, Medicinal , Chemistry , Quality Control , Trace Elements , Reference StandardsABSTRACT
<p><b>OBJECTIVE</b>To analyse the trace elements presented in the same germplasm of Flos Lonicerae with the soil in different producing areas of crude drugs and to investigate, the relationship between the trace elements and the characteristics of the geo-authentic Flos Lonicerae in the soil and crude drugs.</p><p><b>METHOD</b>The analyses on the trace elements of soil and crude drugs were made by ICP-AES.</p><p><b>RESULT</b>The contents of Sr, K, Na, Mg and Ca were higher in the geo-authentic areas, and the contents of Ca, Sr and Fe were higher, but the Cr and Pb were lower in the geo-authentic Flos Lonicerae. The geo-authentic crude drugs had a strong tendency to accumulate P and Cu.</p><p><b>CONCLUSION</b>There are no direct relationship between the concentrations of trace elements in Flos Lonicerae and those in their corresponding soil. There are good relationship between the absorption and accumulation of Ca and Cr, Co, Na and Fe; Zn and Co, Cr, Mn; Na and Co; Mg and Mn.</p>