ABSTRACT
Objective:To investigate the expressions of hypoxia-inducible factor-1α(HIF-1α)and heat shock protein 70(HSP70)in the placenta tissue of the patients with pregnancy-induced hypertension syndrome(PIH), and to elucidate the clinical significances of their expressions in the placenta tissue of the patients with PIH. Methods:Twenty-two cases of placenta tissue of the PIH patients(PIH group)and eighteen cases of placenta tissue of the normal pregnant women(control group)were selected.The expressions of HIF-1αand HSP70 were detected by immunohistochemical method.The differences of potive expressions rates of HIF-1α and HSP70 in placenta tissue of the PIH patients and the normal pregnant women and their relationships in placenta tissue of the PIH patients were analyzed.Results:The positive expression rate of HIF-1α in placenta tissue of the patients in PIH group(81.8%)was higher than that of the normal pregnant women in control group(38.9%)(χ2=7.785,P=0.005),and the positive expression rate of HSP70 in placenta tissue of the patients in PIH group(90.9%)was higher than that of the normal pregnant women in control group(55.6%)(χ2=6.599,P=0.010).Eighteen cases of placenta tissue with HIF-1α positive expression in the PIH patients had HSP70 positive expression(100.0%);among four cases of placenta tissue with HIF-1α negative expression,two cases had HSP70 negative expression (50.0%);their expressions in placenta tissue of the PIH patients had positive correlation(r=0.671,P=0.001). Conclusion:The expressions of HIF-1αand HSP70 in placenta tissue of the PIH patients are higher,and they have positive correlation.
ABSTRACT
Two-dimensional code technology is widely used in daily life,and its application is relatively rare in medical education.Students organized write the Chinese and English slices' information by the way of extracurricular teaching activities,and two-dimensional code transformed from slices' information as label was pasted onto slice to made slice specimen with two-dimensional code.The students can quickly and accurately read the slice information by scanning the two-dimensional code.This practice can stimulate students' interest in learning and creative ability.It not only creates convenient conditions for the opening of the histology experiment and the independent study of the students,but also provides a way of thinking for the information management of the experimental teaching.
ABSTRACT
Objective: To investigate the expressions of hypoxia-inducible factor-la (HIF-la) and heat shock protein 70 (HSP70) in the placenta tissue of the patients with pregnancy-induced hypertension syndrome (PIH), and to elucidate the clinical significances of their expressions in the placenta tissue of the patients with PIH. Methods: Twenty-two cases of placenta tissue of the PIH patients (PIH group) and eighteen cases of placenta tissue of the normal pregnant women (control group) were selected. The expressions of HIF-la and HSP70 were detected by immunohistochemical method. The differences of potive expressions rates of HIF-la and HSP70 in placenta tissue of the PIH patients and the normal pregnant women and their relationships in placenta tissue of the PIH patients were analyzed. Results: The positive expression rate of HIF-1α in placenta tissue of the patients in PIH group (81.8%) was higher than that of the normal pregnant women in control group (38.9%) (χ2=7.785, P= 0.005), and the positive expression rate of HSP70 in placenta tissue of the patients in PIH group 90.9%) was higher than that of the normal pregnant women in control group 55.6%) (χ2=6.599, P=0.010). Eighteen cases of placenta tissue with HIF-la positive expression in the PIH patients had HSP70 positive expression (100.0%); among four cases of placenta tissue with HIF-la negative expression, two cases had HSP70 negative expression 50.0%); their expressions in placenta tissue of the PIH patients had positive correlation (r=0.671, P=0.001). Conclusion: The expressions of HIF-la and HSP70 in placenta tissue of the PIH patients are higher, and they have positive correlation.
ABSTRACT
Objective To explore an effective evaluation method for students' self-and peer-assess-ment. Methods The students of 6 groups participating in extracurricular teaching activities were selected as research subject. Traditional method (final score = mean score of group/2 + teacher's score/2) and mean difference method [final score=teacher's score-(mean difference of group-mean difference of all groups)] were used to calculate final score of each group, and effect of two methods were compared. Results Scores of most groups were higher than the teacher's scores, and high scores were given by group 3 in self- and peer-assessment. The final score of all groups were higher than teacher's scores in traditional method. Compared with teacher's scores, final scores increased significantly in group 1, 4, 5 below mean difference, final score decreased significantly in group 2, 3 above mean difference, and final score did not differ in group 6 equal to mean difference in mean difference method. Conclusion The mean difference method can reflect the effect of student's self- and peer-assessment, and guide student to make objective and accurate evaluation. It is a more reasonable and scientific evaluation method for self-and peer-assessment.
ABSTRACT
The tissue chip is a special tissue section,which has several tens to thousands mini tissues of regular arrangement on the one glass slide.According to the deficiencies in experimental teaching section of morphology at present,the author introduced the characteristics and values of the tissue chip and explored its application prospect in experimental teaching of morphology.