ABSTRACT
Solid papillary carcinoma of the breast is a rare breast papillary lesion that accounts for less than 1％ of breast cancers.The tumor is most common in elderly patients with imaging abnormalities or painless breast masses,histopathological manifestations of solid structure,frequent with mucous and/or neuroendocrine characteristics.The choice of surgical methods is mastectomy and simple mastectomy.At present,it is not well understood by clinicians and pathologists.In this paper,the clinicopathological features,treatment and prognosis of solid papillary carcinoma of the breast diagnosed by pathology in our hospital were retrospectively analyzed in order to improve the further understanding of this disease.
ABSTRACT
Objective To evaluate the effect of driving forces similar to those found in dental plaque fluid on the enamel demineralization and ultrastructure of surface layer.Methods The sections of human enamel were exposed to lactic acid solutions with degree of saturation with respect to enamel and degree of saturation with respect to fluoroapatite for 96 h at 25 ℃,using the deionized water as control in the same conditions.Enamel demineralization was monitored using SEM and confocal laser scanning microscopy(CLSM).Results Only was enamel subsurface demineralization detected in solutions with DS_(EN)(0.1-0.3).Enamel mineral loss and micropores of surface layer decreased significantly with increasing DS_(EN) and DS_(FA) values.However,no mineral loss and micropores of surface layer was observed in sections of enamel exposed to solutions with DS_(EN) values of 0.4 and 0.5,which were covered with homogeneous remineralization layer.Conclusion The demineralization driving forces similar to dental plaque fluid under different DS_(EN) and DS_(FA) have significant effects on the surface layer of enamel and the subsurface demineralization process.