Behcet's Syndrome: Clinical Studies of Thirteen Cases / 대한피부과학회지

Clinical studies on thirteen patients with Behcet's syndrome who had visited during the period from Jan. 1970 to Sep. 1973, to the Department of Dermatology & Ophthahnology, Busan National University Hospital, were made and the following results obtained. 1) The ratio of male vs. female was l. 0: l. 6 with no definite sexual differences. The ages ranged from 17 to 56 years with the peak incidence in third decade of life. 2) The "complete" form consisting of oculo- oro-genital and cutaneous lesions appeared in . 4 patients (30. 8%) and the "incomplet" in 9 patients (69. 2%). 3) Aphthous stomatitis was most predominant, being observed in 12 out of all 13 cases (92.3%), the next was cutaneous manifestations such as erythema nodosum, pyodermas, acneiform & pustular lesions and erythema multiforme in 10 cases (76. 1%) and genital ulcers in 9 cascs (69.2%). Ocular lesions and articular involvements came fourth, each being found in 8 cases (61. 5%). 4) The commonest feature of ocular involvement was relapsing iridocyclitis, being observed in 57. 7% and the disease led to a bilateral loss of vision in 38. 4% 5) Single or combined therapy including corticosteroids and antimicrobials gave transient conservative effects and was of no value to prevent recurrent attacks.

Industrial Ocular Injuries in Busan area

The authors analysed 557 cases of industrial ocular injuries among 27,995 patients seen in the department of ophthalmology, Busan National University Hospital, and three private clinics located in Busan from March 1970 to Feb. 1972. 1. Industrial ocular injuries occupied 24.9% of all ocular injuries. 2. The majorities of industrial ocular injuries were caused by iron piece (49.7%), and flying particles (73.7%). 3. Corneal foreign bodies occupied 59.4% out of all industrial ocular injuries. 4. Industrial ocular injuries frequently occurred in metal and machinary industries- 31.1% in metal product, 13.7% in basic metal and 10.4% in machinary.

A Case of Alveolar Soft Part Sarcoma in the Orbit

Alveolar soft part asrcoma is a primary malignant neoplasm that very rarely occurs in the orbit and it's histogenesis is uncertain. Authors reported a case of alveolar soft part sarcoma occurred primarily in the orbit. The patient, 58 years old Korean male, was admitted to Busan National University Hospital on June 9, 1972 with the chief complaints of the protrusion of the orbital content and pain in the left eye which were gradually developed after receiving enucleation for treatment of the orbital tumor, lasted for 3 months, on Feb. 21, 1972 at local clinic. The patient family history was not contributory. His medical history revealed prior episodes of typhoid fever, liver disease, and a chronic ethanol intake. Physical examination revealed chronic ill appearence in general condition, absent breathing sound at the right lower quadrant of the chest and 3 finger palpable liver. On eye examination, the right eye had good vision and no structual abnormalities, whereas the left side showed anophthalmos, protrusion of the intraorbital content on which surface was rather soft and smooth. We found tortous and dilated superficial skin vessels on the zygomaticotemporal area at which a soft mass was palpated in small fist size. On X-ray studies, there were bony destructive lesion on superior and lateral orbital margin in the skull, atlectatic pattern on the right lower lobe and notching pattern on the right diaphragm in the chest, and other long bone series showed no specific abnormal findings. On liver scanning, mottled areas on the right lower lobe were noted. There were no abnormal findings in C.B.C., urinalysis, C.S.F., stool and blood chemistry. The further studies for the abnormal findings containing liver lesion and atlectatic lung pattern could not perform because of patient's incooperation. We tried the exenteration of left orbit under the general anesthesia on July 8, 1972 but biopsy only performed because the tumor seemed to be extended to pterygoid fossa through the destructed zygomatic bone and to adjacent orbital bone. Histopathological findings showed striking features of alveolar soft part sarcoma; The tumor cells were arrlinged in alveolated or organoid patterns with delicate fibrous band or endothelium lined spaces. The cells were characterized by large, round, oval, and polyhedral cells with rather abundant cytoplasm, which were acidophilic and occasionally contained fine granules and vacuoles in H-E stain. The nuclei were almost located in eccentric, and binucleated, hyperchromatic, anaplastic and occasional mitotic figures were evident.