Reoperation for Rupture of the Porcine Aortic Wall of a Stentless Bioprosthesis / 日本心臓血管外科学会雑誌

A 63-year-old woman presented with pseudoaneurysm formation due to rupture of the porcine aortic wall of the stentless bioprosthesis. She had undergone aortic root replacement using the full root technique with the 25-mm Prima Plus bioprosthesis for annuloaortic ectasia. Congestive heart failure, appearing 65 months after the first surgery, progressed rapidly. Multidetector computed tomography (CT) showed a pseudoaneurysm of the aortic root, and echocardiography revealed severe mitral regurgitation. At reoperation, a large pseudoaneurysm with a 20-mm horizontal tear was seen in the non-coronary sinus of the Prima Plus valve. A repeat aortic root replacement and mitral valve replacement with two mechanical valves were performed. The patient had an uneventful recovery. Histologic examination of the explanted porcine aortic root showed host mononuclear cells and macrophages between the well-stained and poorly stained areas, suggesting that the torn tissue had undergone host-mediated degeneration to some extent. Porcine aortic roots have excellent hemodynamic features, but ruptures in the aortic sinuses of the porcine aortic root have been reported in some cases. Careful follow up with CT or echocardiography is therefore needed after aortic root replacement with stentless bioprostheses.

A Case of Coronary Artery Bypass Grafting for Anomalous Aortic Origin of a Coronary Artery / 日本心臓血管外科学会雑誌

Anomalous aortic origin of a coronary artery (AAOCA) can cause sudden death, especially in young athletes. AAOCA does not have any clinical cardiovascular manifestations and sudden death is often the first manifestation ; hence, it is difficult to diagnose AAOCA before a major episode occurs. We report the case of a 58-year old woman with a right coronary artery arising from the left sinus and passing between the aorta and the pulmonary artery. Although the results of the exercise treadmill test and various other tests were normal, this patient underwent coronary artery bypass, surgery using the right internal thoracic artery to preventing sudden death. Two years after the operation, she is asymptomatic and has normal results on the exercise treadmill test.

Aortic Valve Replacement in Octogenarians : Are Concomitant Coronary Artery Bypass Grafting Operations Predictive Factors ? / 日本心臓血管外科学会雑誌

Because of increasing life expectancy and the high incidence of aortic stenosis (AS) in high-age groups, aortic valve replacement (AVR) for severe AS has become more frequent in recent years. The purpose of this study is to analyze operative outcome in octogenarians and evaluate the effect of concomitant coronary artery bypass grafting (CABG) for coronary artery disease. Between 2003 and 2010, 77 patients (18 men) aged over 80 years (80∼88 years ; mean age, 82.7 years) underwent AVR (bioprosthesis in 75 cases). Of these patients, 43.4% were categorized in New York Heart Association (NYHA) class III∼IV and 41% had a history of congestive heart failure. In addition, 26 patients (33.8%) underwent associated CABG operations (1-4 grafts ; mean, 1.8 grafts) with AVR. Operative mortality was 5.2% (4 patients). The operation time, cardiopulmonary bypass time, and aortic clamp time were significantly longer and amount of blood transfusion needed was greater in the concomitant CABG group than in the AVR-alone group. However, there were no differences between the groups with regard to intensive care unit (ICU) stay, postoperative hospital stay, operative mortality, and long-term survival. The outcome of AVR in octogenarians was good even in concomitant CABG patients. Aggressive surgical treatment of both aortic valve disease and concomitant coronary artery disease is warranted for most patients, despite advanced age.

Aortic Valve Replacement in Octogenarians: Are Concomitant Coronary Artery Bypass Grafting Operations Predictive Factors? / 日本心臓血管外科学会雑誌

Because of increasing life expectancy and the high incidence of aortic stenosis (AS) in high-age groups, aortic valve replacement (AVR) for severe AS has become more frequent in recent years. The purpose of this study is to analyze operative outcome in octogenarians and evaluate the effect of concomitant coronary artery bypass grafting (CABG) for coronary artery disease. Between 2003 and 2010, 77 patients (18 men) aged over 80 years (80∼88 years ; mean age, 82.7 years) underwent AVR (bioprosthesis in 75 cases). Of these patients, 43.4% were categorized in New York Heart Association (NYHA) class III∼IV and 41% had a history of congestive heart failure. In addition, 26 patients (33.8%) underwent associated CABG operations (1-4 grafts ; mean, 1.8 grafts) with AVR. Operative mortality was 5.2% (4 patients). The operation time, cardiopulmonary bypass time, and aortic clamp time were significantly longer and amount of blood transfusion needed was greater in the concomitant CABG group than in the AVR-alone group. However, there were no differences between the groups with regard to intensive care unit (ICU) stay, postoperative hospital stay, operative mortality, and long-term survival. The outcome of AVR in octogenarians was good even in concomitant CABG patients. Aggressive surgical treatment of both aortic valve disease and concomitant coronary artery disease is warranted for most patients, despite advanced age.

Treatment of Patients with Acute Type A Dissection with Malperfusion / 日本心臓血管外科学会雑誌

Although the results of surgical treatment for acute type A dissection have improved because of progress in surgical techniques, the prognosis is still very poor and optimal therapeutic approach is still not clearly established for cases of acute dissection complicated with malperfusion. Of 134 patients who presented with acute aortic dissection between January 1986 and June 1999, 57 had acute type A dissection and 10 had acute type A dissection with malperfusion. Patient age ranged from 53 to 78 (average, 64.6) years. There were 6 men and 4 women. There was accompanying cerebral ischemia in 3 cases, coronary ischemia in 1, visceral ischemia in 5, renal ischemia in 2, ischemia of the extremities in 7, and multiple organ ischemia in 5. One patient died before surgery, and another patient died after sternotomy due to aortic rupture. The other 8 patients underwent surgical operations. The following surgical procedures were performed: bypass grafting to the superior mesenteric artery was performed in 1 patient, stent implantation to the right coronary artery followed by ascending aortic replacement (19th day after onset) was performed in 1, and aortic repair (5 ascending aortic replacements and 1 hemiarch replacement) in the acute phase was performed in 6. The mortality rates were 66.7% (2/3) in patients with cerebral ischemia, 0% (0/1) in the patient with coronary ischemia, 80% (4/5) in those with visceral ischemia, 100% (2/2) in those with renal ischemia, 42.9% (3/7) in those with ischemia of the extremities, 80% (4/5) in those with multiple organ ischemia, and 50% (5/10) in all cases. All patients whose base excess (B.E.) was less than -10mEq/<i>l</i> on admission died (4/4). We conclude that in order to improve surgical results in patients with acute type A dissection with malperfusion, different approaches may be required for each patient. The combination of aortic repair and percutaneous reperfusion are important. Arterial blood gas analyses were simple, and the values of B. E. at admission were useful to determine the surgical strategy in these patients and to predict their prognosis.

High Aortic Occlusion: Surgery and Prognosis / 日本心臓血管外科学会雑誌

From 1976 to 1993, 13 patients with high aortic occlusion were treated surgically. Bypass grafting from infrarenal abdominal aorta to the iliac or femoral arteries was performed in 9 patients, endarterectomy with patch angioplasty in 2, thrombectomy followed by straight graft replacement in 1 and bilateral axillo-femoral artery bypass grafting in 1. In 9 patients, femoro-popliteal run-off was determined by arteriography before or during operation. Occlusion of the femoral artery was detected in two patients, and femoro-popliteal bypass grafting was simultaneously performed with aortic revascularization. Two patients died in the early postoperative period (1: fulminant hepatitis, 1: cerebral infarction), and 4 patients died in the late postoperative period (2: ischemic heart disease, 1: cerebral bleeding, 1: malignant tumor). In one patient the iliac artery occluded 13 years after endarterectomy. All other patients showed patent grafts and satisfactory conditions. In cases of high aortic occlusion, late postoperative results were satisfactory after anatomical revascularization. Ischemic heart disease and cerebral vascular accident were important concerning late complications. Postoperative careful follow-up is necessary.

Arterial Reconstruction for Femoropopliteal Occlusive Disease Due to Arteriosclerosis. A Retrospective Comperative Study between Endarterectomy and Femoropopliteal Bypass / 日本心臓血管外科学会雑誌

During the past thirteen years, 75 patients (97 limbs) with femoropopliteal occulusive disease due to arteriosclerosis were treated by surgical reconstructions. The 75 patients consisted of 70 men and 5 women with an age range of 32-83 years (mean±SD: 65.9±9.6 years). Regarding the indications for operation, intermittent claudication was found in 46 patients (61%), rest pain in 24 patients (32%) and gangrene in 5 patients (7%). As the atherosclerotic risk factors, cigarette smoking and hypertension were present in high rates, and ischemic heart disease was complicated in 31.4%. Endarterectomy with vein angioplasty was performed for 31 limbs and bypass operation usually using EPTFE grafts was for 66 limbs. Cumulative patency rate at five years was 72.6% in endarterectomy group, and 48.1% in bypass group. At ten years, 72.6% and 36.1%. Comparisons of the patency rate between two technics, endarterectomy was significantly better than bypass oparation in late postoperative period. Endarterectomy is recommended as the treatment of choice for femoropopliteal occulusive disease, because of the long-term patency.