1.
Effects of Anaesthesia and Sinoaortic Denervation on the Hypotensive Action of Ketanserin / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12)1985.
Article
in Chinese
| WPRIM
| ID: wpr-550634
ABSTRACT
Effects of anaesthesia and sinoaortic denervation (SAD) on the hypotensive action of , ketanserin were studied in rats. It was found that the dose-effect curves of kelanserin on blood pressure were the same between SAD and sham-operated rats under anaesthesia. However, in concious free ly moving rats, SAD sharpened the dose-effect curves. It is concluded that the lack of hypotensive effect of ketanserin in conscious normotensive animals is due in large part to the integrity of the arterial baroreflex.