ABSTRACT
This case report describes the treatment of an adult female patient with a history of periodontal disease, Class I malocclusion with extrusion, dental spaces, and pathologic tooth migration. The patient was treated with clear aligners, which effectively controlled the strength and direction of orthodontic forces after 3 months of systematic periodontal treatment. The Peer Assessment Rating (PAR) index was calculated from study models before and after treatment. The pretreatment PAR score was 24, and the posttreatment PAR score was 4. The PAR score for this patient changed by 83%. Satisfactory appearance and good function were achieved for this patient.
ABSTRACT
Mesenchymal stem cells ( MSCs) play an important role in skin wound repair because of their multi-directional differentiation potential, hematopoietic support and promotion of stem cell implantation, immune regulation and self-replication. Exosomes contain proteins and RNAs, which have anti-tumor immunity, angiogenesis promotion and other physiological functions. Different MSCs-derived exosomes have different mechanisms in the skin traumatic action. The author summarizes the research progress of different MSCs-derived exosomes in the field of skin tissue repair through elaborations on the traditional treatment methods for skin damage, the biological properties of exosomes, the mechanism of MSCs-derived exosomes in skin wound repair and in other diseases, providing reference for improving clinical repair.
ABSTRACT
Mesenchymal stem cells (MSCs) play an important role in skin wound repair because of their multi-directional differentiation potential, hematopoietic support and promotion of stem cell implantation, immune regulation and self-replication. Exosomes contain proteins and RNAs, which have anti-tumor immunity, angiogenesis promotion and other physiological functions. Different MSCs-derived exosomes have different mechanisms in the skin traumatic action. The author summarizes the research progress of different MSCs-derived exosomes in the field of skin tissue repair through elaborations on the traditional treatment methods for skin damage, the biological properties of exosomes, the mechanism of MSCs-derived exosomes in skin wound repair and in other diseases, providing reference for improving clinical repair.
ABSTRACT
Objective:To evaluate the effect of of twin block appliance in the early treatment of class Ⅱ malocclusion.Methods:20 cases with class Ⅱ malocclusion were treated with Twin block appliance.Cephalometric analysis was used to evaluate the effects.Results:The twin block appliance could stimulate the growth of mandible and lead to retrocline of the upper incisors and procline of the lower incisors.Conclusion:The twin block appliance can achieve remarkable effects of growth modification of dentognathic system.