Bilateral Breast Cancers arising in Peutz-Jeghers Syndrome Patient: A Case Report

Peutz-Jeghers syndrome is an unusual autosomal dominant disorder characterized by gastrointestinal hamartomatous polyps, mucocutaneous pigmentation, and a variety of intestinal and extra-intestinal malignancies. Incidence of breast and gynecologic malignancies is high in women with Peutz-Jeghers syndrome. We describe a case of bilateral breast cancers arising in 22-year-old Peutz-Jeghers syndrome patient.

Complex Cysts of the Breast: Analysis using Sonographic Breast Imaging Reporting and Data System

PURPOSE: The purpose of this study was to evaluate the usefulness of sonographic BI-RADS in differentiation between benignity and malignancy of complex breast cysts. MATERIALS AND METHODS: Among 855 female patients who underwent ultrasound-guided core needle biopsy at our hospital from March 2012 through August 2012, 82 pathologically proven complex cysts detected on ultrasonography were included. The BI-RADS classification was made by radiologists prospectively and the imaging characterization of cystic lesions were classified retrospectively as cystic masses with a thick septa or thick wall, mixed solid and cystic masses, or solid masses with eccentric cystic foci. All lesions examined by ultrasonography were classified prospectively according to the BI-RADS lexicon. The pathologic findings were compared with sonographic appearance. We reviewed and compared the radiologic features between malignant lesions and benign lesions. RESULTS: Finally, according to biopsy results, there were 71 benign and 11 (13.4%) malignant lesions. The frequency of malignancy was significantly higher in solid masses with eccentric cystic foci (p value <0.025). The size of sonographic lesions was significantly larger in malignant lesions than in benign lesions (41.82 mm+/-34.36 vs 18.41 mm+/-16.8 respectively, p=0.049). No statistically significant difference was observed in the sonographic findings according to the BI-RADS lexicon, however, statistically significant difference in final assessment categories was observed between benign and malignant lesions (p value <0.001). CONCLUSIONS: The malignancy rate was higher in cystic lesions with predominantly solid masses and classified as suspicious malignancy using the BI-RADS lexicon.

A Case of an Abdominal Wall Abscess Associated with Spilled Gallstones: Imaging Findings and Clinical Significance

Laparoscopic cholecystectomy (LC) has been the gold standard for symptomatic gall stones for the last 20 years. The spillage of stones is reported in up to one-third of all LCs but clinical squeals caused by dropped gallstones are uncommon. We recently observed a patient with late abdominal wall abscess formation as a result of dropped gall stones after LC, who in the end, underwent open surgery because the medical therapy including antibiotics and percutaneous catheter drainage was not fully effective.

18F-FDG PET/CT in Primary AL Hepatic Amyloidosis Associated with Multiple Myeloma

We report here on a rare case of primary AL hepatic amyloidosis associated with multiple myeloma in a 64-year-old woman. The patient was referred for evaluating her progressive jaundice and right upper quadrant pain. 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) showed diffusely and markedly increased 18F-FDG uptake in the liver. Although there have been several case studies showing positive 18F-FDG uptake in pulmonary amyloidosis, to the best of our knowledge, the 18F-FDG PET/CT findings of hepatic amyloidosis or primary hepatic amyloidosis associated with multiple myeloma have not been reported previously.